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O2881

盐酸奥昔布宁

Name: 盐酸奥昔布宁
Brand: SIGMA

≥98% (TLC), Muscarinic acetylcholine receptor antagonist, powder

别名:

α-苯基环己烷乙醇酸 4-(二乙基氨基)-2-丁炔酯盐酸盐

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关于此项目

经验公式（希尔记法）:

C₂₂H₃₁NO₃ · HCl

化学文摘社编号:

1508-65-2

分子量:

393.95

NACRES:

NA.77

PubChem Substance ID:

57654480

UNSPSC Code:

12352200

EC Number:

216-139-7

MDL number:

MFCD00072150

Assay:

≥98% (TLC)

Form:

powder

Quality level:

200

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属性

产品名称

盐酸奥昔布宁, ≥98% (TLC), powder

Quality Level

200

assay

≥98% (TLC)

form

powder

color

white

solubility

H₂O: 50 mg/mL

originator

Johnson & Johnson

SMILES string

Cl.CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c2ccccc2

InChI

1S/C22H31NO3.ClH/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20;/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3;1H

InChI key

SWIJYDAEGSIQPZ-UHFFFAOYSA-N

Gene Information

human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

说明

Biochem/physiol Actions

毒蕈碱型乙酰胆碱受体拮抗剂。

毒蕈碱型乙酰胆碱受体拮抗剂；可能通过下调生长促进基因，抑制膀胱平滑肌细胞的增殖。

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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Early administration of oxybutynin improves bladder function and clinical outcomes in newborns with posterior urethral valves.

Jessica T Casey et al.

The Journal of urology, 188(4 Suppl), 1516-1520 (2012-08-23)

Abnormal bladder function following posterior urethral valve ablation can lead to deleterious effects on renal function and urinary continence. We performed a pilot study to determine if bladder dysfunction could be ameliorated by the early administration of oxybutynin. We enrolled

Bryophyllum pinnatum inhibits detrusor contractility in porcine bladder strips--a pharmacological study towards a new treatment option of overactive bladder.

V Schuler et al.

Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(10), 947-951 (2012-07-25)

A broad spectrum of synthetic agents is available for the treatment of overactive bladder. Anti-cholinergic drugs show a poor compliance due to side effects. There is an increasing use of plant extracts in medicine. We have therefore investigated the inhibitory

Application drying time for oxybutynin chloride topical gel.

Diane K Newman et al.

Urologic nursing, 32(5), 265-269 (2013-03-12)

This study determined the median drying time for oxybutynin chloride topical gel (OTG) approved for treatment of overactive bladder was 3.1 minutes, Most participants reported positive perceptions of OTG attributes.

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O2881-1G	04061834227212
O2881-5G	04061832092454
O2881-500MG	04061832092447