O9126
Oxotremorine sesquifumarate salt
≥98% (HPLC), solid
别名:
1-(4-[1-Pyrrolidinyl]-2-butynyl)-2-pyrrolidinone, 1-(4-[1-Pyrrolidinyl]2-butynyl)-2-pyrrolidinone
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关于此项目
经验公式（希尔记法）:
C12H18N2O · 1.5C4H4O4 · xH2O
化学文摘社编号:
分子量:
380.39 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
241-388-3
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
assay
≥98% (HPLC)
form
solid
mp
102-105 °C (lit.)
solubility
H2O: >10 mg/mL
storage temp.
2-8°C
SMILES string
[H]\C(=C(\[H])C(O)=O)C(O)=O.[H]\C(=C(\[H])C(O)=O)C(O)=O.[H]\C(=C(\[H])C(O)=O)C(O)=O.O=C1CCCN1CC#CCN2CCCC2.O=C3CCCN3CC#CCN4CCCC4
InChI
1S/2C12H18N2O.3C4H4O4/c2*15-12-6-5-11-14(12)10-4-3-9-13-7-1-2-8-13;3*5-3(6)1-2-4(7)8/h2*1-2,5-11H2;3*1-2H,(H,5,6)(H,7,8)/b;;3*2-1+
InChI key
WLYYOFJEBGHKEC-VQYXCCSOSA-N
Gene Information
human ... CHRM2(1129)
Biochem/physiol Actions
Oxotremorine sesquifumarate salt is a muscarinic acetylcholine receptor agonist with preference for the M2 receptor.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
I B Introini-Collison et al.
Behavioral and neural biology, 57(3), 248-255 (1992-05-01)
Post-training administration of the centrally acting muscarinic agonist oxotremorine (50.0 microgram/kg, ip) facilitated 48-hr retention, in mice, of a one-trial step-through inhibitory avoidance response. Oxotremorine-induced memory facilitation was not prevented by the simultaneous post-training administration of the central beta-adrenoceptor antagonist
J D Brioni et al.
Behavioral and neural biology, 50(3), 251-254 (1988-11-01)
The pre-test administration of beta-endorphin (0.05 microgram/mouse), oxotremorine sesquifumarate (5.0 micrograms/mouse), or beta-endorphin plus oxotremorine enhanced retention test performance of a conditioned emotional response in mice. The effects were blocked by scopolamine. Scopolamine had no effect of its own. The
P G Gunasekar et al.
Neuroscience research, 49(1), 13-18 (2004-04-22)
Cyanide is generated in neurons and this report examines the two different receptors which mediate cyanide formation in neuronal tissue. An opiate receptor blocked by naloxone increases cyanide production both in rat brain and in rat pheochromocytoma (PC12) cells. A
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| O9126-100MG | 04061832083421 |
| O9126-500MG | 04061834248781 |
| O9126-1G | 04061825982588 |