P5173
pGlu-3-Methyl-His-Pro Amide
≥97% (HPLC)
别名:
(His[T-Me])-TRH, [3-Methyl-His2]-Thyrotropin releasing hormone
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关于此项目
经验公式（希尔记法）:
C17H24N6O4
化学文摘社编号:
分子量:
376.41
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Biochem/physiol Actions
Analog of thyrotropin releasing hormone (TRH) that is ten-times more potent than TRH in releasing thyrotropin (TSH) from the anterior pituitary.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
G Vita et al.
Experimental brain research, 83(2), 381-384 (1991-01-01)
The autoradiographic localization of thyrotropin-releasing hormone (TRH) receptors was investigated in the rat spinal cord after transection at the level of T8-T9. The discrete distribution of [3H]-MeTRH binding was measured with a computerized image analyzer at the cervical (C6-C7) and
Modulation of GABAA receptor channels and calcium currents in cultured porcine melanotrophs.
R Schlichter et al.
Annals of the New York Academy of Sciences, 680, 199-210 (1993-05-31)
Michael C Veronesi et al.
Brain research, 1128(1), 79-85 (2006-11-28)
TRH has been found to be efficacious in treating certain neurodegenerative disorders such as epilepsy, Alzheimer's disease, neurotrauma and depression, however, its mechanism of action is poorly understood. Since glutamate (Glu) toxicity has been implicated in these disorders, we utilized