P5173
pGlu-3-Methyl-His-Pro Amide
≥97% (HPLC)
别名:
(His[T-Me])-TRH, [3-Methyl-His2]-Thyrotropin releasing hormone
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关于此项目
经验公式（希尔记法）:
C17H24N6O4
化学文摘社编号:
分子量:
376.41
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Biochem/physiol Actions
Analog of thyrotropin releasing hormone (TRH) that is ten-times more potent than TRH in releasing thyrotropin (TSH) from the anterior pituitary.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
C Petrou et al.
The Journal of biological chemistry, 272(4), 2326-2333 (1997-01-24)
To determine whether functional receptor-G protein coupling or signaling are required for internalization of the thyrotropin-releasing hormone receptor (TRHR), we compared the endocytosis of Gq-coupled and uncoupled receptors. A hemagglutinin epitope-tagged TRHR (HA-TRHR) was in the Gq-coupled state when bound
N A Sharif et al.
Neuroscience letters, 104(1-2), 183-188 (1989-09-25)
The equilibrium receptor binding properties and the pharmacological specificity of the spinal receptors for thyrotropin-releasing hormone (TRH) were determined. [3H]MeTRH bound to a single class of high-affinity (dissociation constant, KdS = 5.0; 6.0 and 5.5 nM), saturable (Bmax = 21.5
N H Rahmani et al.
Pharmacology, 43(3), 156-162 (1991-01-01)
The effect of delta- and kappa-opiate receptor agonists on the binding of 3H-(3-MeHis2) thyrotropin-releasing hormone (3H-MeTRH) to membranes of the spinal cord and amygdala of male Sprague-Dawley rats was determined in an effort to further understand interactions between opiates and