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R8656

Anti-Peroxiredoxin 2 (C-terminal) antibody produced in rabbit

Name: Anti-Peroxiredoxin 2 (C-terminal) antibody produced in rabbit
Brand: SIGMA

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

别名:

Anti-NKEFB, Anti-Natural killer-enhancing factor B, Anti-PRDX2, Anti-TDPX1, Anti-Thiol-specific antioxidant 1, Anti-Thioredon peroxidase 1, Anti-Torin

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About This Item

UNSPSC代码:

12352203

NACRES:

NA.41

生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

antigen ~22 kDa

种属反应性

rat, human, mouse

浓度

~1.0 mg/mL

技术

immunoprecipitation (IP): 2.0-5.0 μg using lysate of mouse 3T3 cells
western blot: 0.5-1.0 using whole extract of human HeLa cells
western blot: 1-2 μg/mL using whole extract of rat NRK cells

UniProt登记号

P32119

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... PRDX2(7001)
mouse ... Prdx2(21672)
rat ... PRDX2(29338)

一般描述

Peroxiredoxin 2 is a cytosolic member of the peroxiredoxin family of antioxidant enzymes. All peroxiredoxin enzymes exist as homodimers, they contain a conserved Cys residue corresponding to Cys51 in mammalian peroxiredoxin 1 and 2 and are distributed differentially within cells.

免疫原

synthetic peptide corresponding to amino acid residues 184-198 of human peroxiredoxin 2 conjugated to KLH. The corresponding sequence is identical in rat and mouse peroxiredoxin 2.

应用

Anti-Peroxiredoxin 2 (C-terminal) antibody produced in rabbit has been used in immunoblottingand immunoprecipitation.

生化/生理作用

Peroxiredoxin 2 has dual roles as a peroxireductase in moderately oxidative conditions and as a molecular chaperone that binds and protects denatured proteins in hyper-oxidative conditions. Peroxiredoxin 2 is involved in platelet-derived growth factor (PDGF) and tumor necrosis factor (TNF) signaling regulation and is elevated in several human cancers and neurodegenerative disorders.

外形

Solution in 0.01 M phophate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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