Anti-HVCN1 antibody produced in rabbit

Hydrogen voltage gated channel 1 (HVCN1) is a voltage gated proton channel and is needed for efflux of intracellular acid. The gene encoding it is localized on human chromosome 12q24.11.

HVCN1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human HVCN1.

Hydrogen voltage gated channel 1 (HVCN1) modulates insulin secretion by participating in Ca²⁺ homeostasis. In mice, the channel is involved in superoxide generation, bacterial removal from granulocytes and neutrophils and superoxide-associated B-cell receptor (BCR) signaling. HVCN1 might be associated with BCR-mediated B-cell malignancies.

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Supplied in PBS with 0.02% sodium azide.

The action of this antibody can be blocked using blocking peptide SBP3500536.

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