SAB3700764
抗- 猴IgG（γ-链特异性） 山羊抗
affinity isolated antibody, buffered aqueous solution
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关于此项目
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IHC, WB
Citations:
4
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
monkey
concentration
1.0 mg/mL
technique(s)
immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
General description
免疫球蛋白G（IgG）有150kDa的单体结构，具有两条相同的重链和两条相同的轻链，分子量分别为50kDa和25kDa。该抗体的一级结构还包含连接两条重链、连接重链和轻链，并位于链内的二硫键。IgG 可进一步分为四种亚型，即IgG1、IgG2、IgG3 和 IgG4，而这四种亚型所含的不同重链分别称为 γ1、 γ2、 γ3 和 γ4。母体IgG是唯一能通过胎盘转运至胎儿的抗体。它对婴儿进行被动免疫。
抗体类型：IgG
Immunogen
猴IgGγ重链
Biochem/physiol Actions
本产品采用单特异性抗血清，通过免疫亲和色谱法制备，使用猴IgG偶联琼脂糖珠，然后进行固相吸附，以去除任何不希望的反应。通过免疫电泳分析，产生了针对抗山羊血清、猴IgG和猴血清的单一沉淀弧。未观察到针对猴IgM或猴IgA的反应。
Physical form
以0.02 M磷酸钾、0.15 M氯化钠（pH 7.2）溶液供应
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Peter Ulrichts et al.
The Journal of clinical investigation, 128(10), 4372-4386 (2018-07-25)
Intravenous Ig (IVIg), plasma exchange, and immunoadsorption are frequently used in the management of severe autoimmune diseases mediated by pathogenic IgG autoantibodies. These approaches modulating IgG levels can, however, be associated with some severe adverse reactions and a substantial burden
Akiko Ishii et al.
Molecular therapy. Methods & clinical development, 18, 44-49 (2020-06-25)
To establish an efficient, safe immunosuppressive regimen of adeno-associated vector (AAV)-mediated gene therapy for Duchenne muscular dystrophy (DMD), we evaluated the effect of tacrolimus (FK506) on skeletal muscle transduction with AAV8 and AAV9 vectors expressing the LacZ and microdystrophin (M3)
Human placental Fc receptors and the transmission of antibodies from mother to fetus.
Simister NE and Story CM
Journal of Reproductive Immunology, 37(1), 1-23 (1997)
Antibody structure, instability, and formulation.
Wang W
Journal of Pharmaceutical Sciences, 96(1), 1-26 (2007)
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