SAB4500248
Anti-DJ-1 antibody produced in rabbit
affinity isolated antibody
别名:
Oncogene DJ1, PARK7, Parkinson disease protein 7, Protein DJ-1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC, WB
Citations:
5
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 19 kDa
species reactivity
mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PARK7(11315)
General description
Anti-DJ-1 Antibody detects endogenous levels of total DJ-1 protein.
DJ-1 (protein deglycase)/PARK7 (parkinsonism associated deglycase) is an oncogene, made of 189 amino acids. It is present in several human tissues and is located on chromosome 1p36.
Immunogen
The antiserum was produced against synthesized peptide derived from human DJ-1.
Immunogen Range: 21-70
Immunogen Range: 21-70
Application
Anti-DJ-1 antibody has been used in western blotting.
Biochem/physiol Actions
In lung cancer patients, DJ-1 (protein deglycase) acts as a biomarker for the initial prognosis. It also acts as a serum biomarker for identifying high-risk endometrial cancer.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
DJ-1 as a potential biomarker for the early diagnosis in lung cancer patients
Han B, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(6) (2017)
DJ-1 is a reliable serum biomarker for discriminating high-risk endometrial cancer
Di Cello A, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(6) (2017)
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36
van Duijn CM, et al.
American Journal of Human Genetics, 69(3), 629-634 (2001)
Lin Cheng et al.
Experimental and therapeutic medicine, 21(6), 557-557 (2021-04-15)
Studies have confirmed that DJ-1 is associated with diseases associated with the nervous system, including Alzheimer's disease (AD). However, the role of DJ-1 in the pathogenesis of AD has not been clarified. To investigate the effect of DJ-1 on brain
Kuldip D Dave et al.
Neurobiology of disease, 70, 190-203 (2014-06-28)
Recessively inherited loss-of-function mutations in the PTEN-induced putative kinase 1(Pink1), DJ-1 (Park7) and Parkin (Park2) genes are linked to familial cases of early-onset Parkinson's disease (PD). As part of its strategy to provide more tools for the research community, The
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