SAB4500560
Anti-GDF7 antibody produced in rabbit
affinity isolated antibody
别名:
GDF-7, Growth/differentiation factor 7
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 46 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... GDF7(151449)
General description
BMPs (bone morphogenetic proteins) belong to the transforming growth factor-β (TGF-β) superfamily of structurally related signaling proteins. BMP-12 is highly conserved across species. The gene encoding this protein is localized on human chromosome 2. Anti-GDF7 Antibody detects endogenous levels of total GDF7 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human GDF7.
Immunogen Range: 191-240
Immunogen Range: 191-240
Biochem/physiol Actions
As implied by their name, BMPs (bone morphogenetic proteins) promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. It also has a role in seminal vesicle development.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk.
Becker J
Cancer Medicine, 5(5), 888-891 (2016)
The family of bone morphogenetic proteins.
Ducy P and Karsenty G
Kidney International, 57(6), 2207-2214 (2000)
Bone Morphogenetic Protein (BMP) signaling in development and human diseases.
Wang RN
Genes & Development, 1(1), 87-105 (2014)
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