SAB4700742
Monoclonal Anti-Notch 1 antibody produced in mouse
clone mN1A, purified immunoglobulin, buffered aqueous solution
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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
mN1A, monoclonal
Application:
FACS, ICC, IHC, IP
Citations:
2
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
mN1A, monoclonal
form
buffered aqueous solution
species reactivity
human, mouse
concentration
1 mg/mL
technique(s)
flow cytometry: suitable, immunoblotting: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
Quality Level
Gene Information
human ... NOTCH1(4851)
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
General description
The mouse monoclonal antibody mN1A recognizes intracellular domain of Notch 1 protein, mainly its activated form. The unprocessed Notch 1 protein is recognized with lower affinity.
Immunogen
GST fusion protein containing cdc10-NCR region of mouse Notch1
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Emanuele Brai et al.
Frontiers in cellular neuroscience, 9, 447-447 (2015-12-05)
Notch signaling plays a crucial role in adult brain function such as synaptic plasticity, memory and olfaction. Several reports suggest an involvement of this pathway in neurodegenerative dementia. Yet, to date, the mechanism underlying Notch activity in mature neurons remains
S Marathe et al.
Cell death and differentiation, 22(11), 1775-1784 (2015-03-31)
Neurological disorders such as Alzheimer's disease, stroke and epilepsy are currently marred by the lack of effective treatments to prevent neuronal death. Erroneous cell cycle reentry (CCR) is hypothesized to have a causative role in neurodegeneration. We show that forcing
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