recombinant
expressed in HEK 293 cells
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
RM192, monoclonal, recombinant monoclonal
form
buffered aqueous glycerol solution
species reactivity
human
technique(s)
ELISA: 0.5-2 μg/mL, immunocytochemistry: 0.005-0.1 μg/mL, immunohistochemistry: 0.005-0.1 μg/mL, western blot: 0.01-1 μg/mL
isotype
IgG
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
mutation (Lys27Met)
Gene Information
human ... H3C1(8350)
Immunogen
对应于组蛋白H3 K27M突变体的肽。
Biochem/physiol Actions
该抗体可与组蛋白H3 K27M突变体反应。与野生型组蛋白H3无交叉反应性。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多信息。
Physical form
溶于含有50%甘油、1%BSA和0.09%叠氮化钠的磷酸盐缓冲盐水中。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 2
法规信息
常规特殊物品
含少量动物源组分生物产品
低风险生物材料
此项目有
Angela N Viaene et al.
Brain pathology (Zurich, Switzerland), 31(1), 45-60 (2020-07-19)
Congenital brain tumors are rare accounting for 0.5%-1.9% of all pediatric brain tumors. While different criteria have been used to classify a tumor as congenital, those diagnosed prior to 6 months of age are considered to be "probably" congenital in origin.
N Kfoury-Beaumont et al.
BMC biology, 20(1), 124-124 (2022-06-01)
Neurodevelopmental disorders increase brain tumor risk, suggesting that normal brain development may have protective properties. Mutations in epigenetic regulators are common in pediatric brain tumors, highlighting a potentially central role for disrupted epigenetic regulation of normal brain development in tumorigenesis.
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