SMB01046
Phomopsolide B
≥90% (LC/MS-ELSD)
别名:
(+)-Phomopsolide B, 2-Butenoic acid, 2-methyl-, (2S,3S)-2-[(1E,3S,4S)-3,4-dihydroxy-1-pentenyl]-3,6-dihydro-6-oxo-2H-pyran-3-yl ester, (2E)- (9CI)
SMILES string
O1[C@H]([C@H](C=CC1=O)OC(=O)\C(=C\C)\C)\C=C\[C@H](O)[C@@H](O)C
InChI
1S/C15H20O6/c1-4-9(2)15(19)21-13-7-8-14(18)20-12(13)6-5-11(17)10(3)16/h4-8,10-13,16-17H,1-3H3/b6-5+,9-4+/t10-,11-,12-,13-/m0/s1
InChI key
JTHHOHSDOJJNFN-HIWLEQICSA-N
biological source
plant
assay
≥90% (LC/MS-ELSD)
form
solid
mol wt
296.32
solubility
water: soluble
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
General description
Phomopsolide B is a phytotoxin, a natural bioactive compound commonly derived from Penicillium sp. but also reported in Diaporthe phaseolorum and Phomopsis sp. fungi. It has demonstrated the ability to induce apoptosis in cancer cells, inhibit the growth of bacteria and fungi, and modulate immune responses. This secondary metabolite exhibits various biological activities, including antifungal, antibacterial, and anticancer properties.
Application
It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
Features and Benefits
- High quality compound suitable for multiple research applications
- Compatible with HPLC and mass spectrometry techniques
Other Notes
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Andrea A Stierle et al.
Natural product communications, 9(1), 87-90 (2014-03-26)
For the past fifteen years we have studied the secondary metabolites of extremophilic fungi from the Berkeley Pit, an abandoned acid mine waste lake. Fungi associated with an acid-tolerant alga have also been harvested from the Pit. Penicillium clavigerum Demelius
D B Stierle et al.
Journal of natural products, 60(11), 1207-1209 (1997-12-11)
Investigation of the bioactive compounds from a Penicillium sp. isolated from the inner bark of the Pacific yew, Taxus brevifolia, led to the isolation of the known furanone 1, and a series of phomopsolides. The phomopsolide fractions contained phomopsolides A
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