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T4446

N-乙酰-L-酪氨酸

Name: <I>N-乙酰-L-酪氨酸
Brand: SIGMA

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关于此项目

线性分子式:

4-(HO)C₆H₄CH₂CH(NHCOCH₃)CO₂H

化学文摘社编号:

537-55-3

分子量:

223.23

EC Number:

208-671-3

UNSPSC Code:

12352209

NACRES:

NA.26

Beilstein/REAXYS Number:

2697172

MDL number:

MFCD00037190

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属性

biological source

non-animal source

assay

≥98.5%

form

crystalline powder

manufacturer/tradename

Ajinomoto

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, tested

mp

149-152 °C (lit.)

solubility

H₂O: 25 mg/mL

application(s)

pharmaceutical (small molecule)

SMILES string

CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C11H13NO4/c1-7(13)12-10(11(15)16)6-8-2-4-9(14)5-3-8/h2-5,10,14H,6H2,1H3,(H,12,13)(H,15,16)/t10-/m0/s1

InChI key

CAHKINHBCWCHCF-JTQLQIEISA-N

说明

General description

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

Application

L-Tyrosine is a non-essential amino acid. It can be used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. N-Acetyl-L-tyrosine is an acetylated derivative of the essential amino acid L-tyrosine with reported improved nutritional properties.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthesis and evaluation of N-acetyl-L-tyrosine based compounds as PPARalpha selective activators.

Rakesh Kumar et al.

European journal of medicinal chemistry, 42(4), 503-510 (2006-12-26)

The development of type 2 diabetes in obese individuals is linked to lipid accumulation in non-adipose tissues. A series of N-acetyl-L-tyrosine derivatives were synthesized and evaluated for PPAR transactivation. Compounds 4d and 4f were found to show better PPARalpha transactivation

[Recording the delta-pH-generating biochemical reactions by light-addressed sensors with Ta2O5 dielectrics].

A N Reshetilov et al.

Doklady Akademii nauk, 342(5), 700-702 (1995-06-01)

Solution interactions between the uranyl cation [UO2(2+)] and histidine, N-acetyl-histidine, tyrosine, and N-acetyl-tyrosine.

Wei Xie et al.

Journal of inorganic biochemistry, 103(1), 58-63 (2008-10-25)

Complexes of the uranyl cation [UO(2)(2+)] with histidine (His), N-acetyl-histidine (NAH), tyrosine (Tyr), and N-acetyl-tyrosine (NAT) were studied by UV-visible and NMR spectroscopy, and by potentiometric titration. Protonation constants for each ligand are reported, as are cumulative formation constants for

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全球贸易项目编号

货号	GTIN
T4446-100G	04061837346125
T4446-1KG	04061834417507
T4446-25KG	04061834432630
T4446-10KG	04061834432623