生物来源
non-animal source
方案
≥98.5%
表单
crystalline powder
制造商/商品名称
Ajinomoto
技术
cell culture | mammalian: suitable
杂质
endotoxin, heavy metals, tested
mp
149-152 °C (lit.)
溶解性
H2O: 25 mg/mL
应用
pharmaceutical (small molecule)
SMILES字符串
CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
InChI
1S/C11H13NO4/c1-7(13)12-10(11(15)16)6-8-2-4-9(14)5-3-8/h2-5,10,14H,6H2,1H3,(H,12,13)(H,15,16)/t10-/m0/s1
InChI key
CAHKINHBCWCHCF-JTQLQIEISA-N
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一般描述
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.
应用
L-Tyrosine is a non-essential amino acid. It can be used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. N-Acetyl-L-tyrosine is an acetylated derivative of the essential amino acid L-tyrosine with reported improved nutritional properties.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
J P Eiserich et al.
The Journal of biological chemistry, 271(32), 19199-19208 (1996-08-09)
Detection of 3-nitrotyrosine has served as an in vivo marker for the production of the cytotoxic species peroxynitrite (ONOO-). We show here that reaction of nitrite (NO2-), the autoxidation product of nitric oxide (.NO), with hypochlorous acid (HOCl) forms reactive
Justyna Mrozek et al.
Biophysical chemistry, 111(2), 105-113 (2004-09-24)
The steady-state and time-resolved fluorescence spectroscopy was applied to determine the influence of an alkyl substituent(s) (methyl or ethyl, n-propyl, iso-propyl, n-butyl, sec-butyl, or t-butyl) on amide nitrogen atom on photophysical properties of tyrosine and N-acetyltyrosine amides in water. Generally
Ming-Chou Chiang et al.
The Turkish journal of pediatrics, 50(5), 492-494 (2008-12-24)
Restrictive dermopathy is a rare and lethal autosomal recessive genodermatosis characterized by tight skin, typical dysmorphic face, generalized arthrogryposis and pulmonary hypoplasia. Infants with restrictive dermopathy have similar findings in skin biopsy, but other abnormalities are unremarkable. We report a
G Drabik et al.
Acta biochimica Polonica, 48(1), 271-275 (2001-07-07)
N-acetyl-L-tyrosine (N-acTyr), with the alpha amine residue blocked by acetylation, can mimic the reactivity of exposed tyrosyl residues incorporated into polypeptides. In this study chlorination of N-acTyr residue at positions 3 and 5 in reactions with NaOCl, chloramines and the
Wei Xie et al.
Journal of inorganic biochemistry, 103(1), 58-63 (2008-10-25)
Complexes of the uranyl cation [UO(2)(2+)] with histidine (His), N-acetyl-histidine (NAH), tyrosine (Tyr), and N-acetyl-tyrosine (NAT) were studied by UV-visible and NMR spectroscopy, and by potentiometric titration. Protonation constants for each ligand are reported, as are cumulative formation constants for
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