WH0161582M9
Monoclonal Anti-DYX1C1 antibody produced in mouse
clone 6G1, purified immunoglobulin, buffered aqueous solution
别名:
Anti-DYX1, Anti-DYXC1, Anti-EKN1, Anti-FLJ37882, Anti-MGC70618, Anti-dyslexia susceptibility 1 candidate 1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
6G1, monoclonal
Application:
ELISA (i), IF, IP, WB
Citations:
4
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
6G1, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunofluorescence: suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL
isotype
IgG2aκ
GenBank accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... DYX1C1(161582)
General description
Dyslexia susceptibility 1 candidate 1 (DYX1C1) is a 420 amino acid protein. The gene encoding it localized on human chromosome 15q21 and consists of 10 exons.
Immunogen
DYX1C1 (NP_570722, 336 a.a. ~ 420 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTELKS
Sequence
KLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTELKS
Biochem/physiol Actions
Dyslexia susceptibility 1 candidate 1 (DYX1C1) associates with estrogen receptors. It has a role in neuronal migration and has been linked to developmental dyslexia.
Physical form
Solution in phosphate buffered saline, pH 7.4
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
此项目有
C Tran et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 162B(2), 146-156 (2013-01-24)
Reading disabilities (RD) have a significant genetic basis and have shown linkage to multiple regions including chromosome 15q. Dyslexia susceptibility 1 candidate gene 1 (DYX1C1) on chromosome 15q21 was originally proposed as a candidate gene with two potentially functional polymorphisms
Shyamala K Venkatesh et al.
Psychiatric genetics, 24(1), 10-20 (2013-12-24)
DYX1C1 has been identified as a susceptible candidate gene for developmental dyslexia (DD); studies in various populations have yielded inconclusive results and the causal allele is unknown in the Indian population. On the basis of the initial association studies and
T C Bates et al.
Molecular psychiatry, 15(12), 1190-1196 (2009-11-11)
The status of DYX1C1 (C15q21.3) as a susceptibility gene for dyslexia is unclear. We report the association of this gene with reading and spelling ability in a sample of adolescent twins and their siblings. Family-based association analyses were carried out
Gustaf Rosin et al.
BMC cancer, 12, 79-79 (2012-03-02)
The dyslexia candidate gene, DYX1C1, shown to regulate and interact with estrogen receptors and involved in the regulation of neuronal migration, has recently been proposed as a putative cancer biomarker. This study was undertaken to assess the prognostic value and
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