WH0161582M9
Monoclonal Anti-DYX1C1 antibody produced in mouse
clone 6G1, purified immunoglobulin, buffered aqueous solution
别名:
Anti-DYX1, Anti-DYXC1, Anti-EKN1, Anti-FLJ37882, Anti-MGC70618, Anti-dyslexia susceptibility 1 candidate 1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
6G1, monoclonal
Application:
ELISA (i), IF, IP, WB
Citations:
4
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
6G1, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunofluorescence: suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL
isotype
IgG2aκ
GenBank accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... DYX1C1(161582)
General description
Dyslexia susceptibility 1 candidate 1 (DYX1C1) is a 420 amino acid protein. The gene encoding it localized on human chromosome 15q21 and consists of 10 exons.
Immunogen
DYX1C1 (NP_570722, 336 a.a. ~ 420 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTELKS
Sequence
KLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTELKS
Biochem/physiol Actions
Dyslexia susceptibility 1 candidate 1 (DYX1C1) associates with estrogen receptors. It has a role in neuronal migration and has been linked to developmental dyslexia.
Physical form
Solution in phosphate buffered saline, pH 7.4
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
此项目有
C Tran et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 162B(2), 146-156 (2013-01-24)
Reading disabilities (RD) have a significant genetic basis and have shown linkage to multiple regions including chromosome 15q. Dyslexia susceptibility 1 candidate gene 1 (DYX1C1) on chromosome 15q21 was originally proposed as a candidate gene with two potentially functional polymorphisms
Shyamala K Venkatesh et al.
Psychiatric genetics, 24(1), 10-20 (2013-12-24)
DYX1C1 has been identified as a susceptible candidate gene for developmental dyslexia (DD); studies in various populations have yielded inconclusive results and the causal allele is unknown in the Indian population. On the basis of the initial association studies and
Gustaf Rosin et al.
BMC cancer, 12, 79-79 (2012-03-02)
The dyslexia candidate gene, DYX1C1, shown to regulate and interact with estrogen receptors and involved in the regulation of neuronal migration, has recently been proposed as a putative cancer biomarker. This study was undertaken to assess the prognostic value and
T C Bates et al.
Molecular psychiatry, 15(12), 1190-1196 (2009-11-11)
The status of DYX1C1 (C15q21.3) as a susceptibility gene for dyslexia is unclear. We report the association of this gene with reading and spelling ability in a sample of adolescent twins and their siblings. Family-based association analyses were carried out
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