Z0167
玉米赤霉酮
≥98% (TLC), mycotoxin, powder
别名:
2,4-二羟基-6-（10-羟基-6-氧代十一烷基）苯甲酸 μ-内酯
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关于此项目
经验公式（希尔记法）:
C18H24O5
化学文摘社编号:
分子量:
320.38
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
玉米赤霉酮,
sterility
non-sterile
Quality Level
assay
≥98% (TLC)
form
powder
solubility
methanol: 9.80-10.20 mg/mL, clear, colorless
shipped in
ambient
storage temp.
−20°C
SMILES string
C[C@H]1CCCC(=O)CCCCCc2cc(O)cc(O)c2C(=O)O1
InChI
1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,20-21H,2-9H2,1H3/t12-/m0/s1
InChI key
APJDQUGPCJRQRJ-LBPRGKRZSA-N
Gene Information
rat ... Ar(24208)
General description
玉米赤霉酮(Zearalanone, ZEA) ，又称F-2毒素，是由各种镰刀菌产生的非甾体雌性真菌毒素。禾谷镰刀菌Fusarium graminearum被认为是玉米赤霉酮的主要生产菌种。它常见于发霉的干草、高水分含量的玉米、收割前感染的玉米。
Application
玉米赤霉酮已用于：
- 作为真菌毒素研究其对青春期前母犬中卵巢组织学的影响
- 作为真菌毒素研究其对母犬中免疫学、血液学和生化选定指数的影响
- 作为标准品建立校准曲线，用于研究其对青春期前雌性比格犬外周血中黄体酮与17β-雌二醇浓度和体重的影响
- 作为标准品建立校准曲线，用于研究其在生殖道瘤样病变女性中的毒性水平
Biochem/physiol Actions
玉米赤霉酮被认为会导致猪的外阴阴道炎和雌激素反应。
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
高风险级别生物产品--毒素类产品
此项目有
Mathias Devreese et al.
Journal of agricultural and food chemistry, 63(20), 5092-5098 (2015-05-08)
After oral (PO) and intravenous (IV) administration of zearalenone (ZEN) to broiler chickens, laying hens, and turkey poults, the mycotoxin was rapidly absorbed (Tmax = 0.32-0.97 h) in all three species; however, the absolute oral bioavailability was low (F% =
Łukasz Zielonka et al.
Toxins, 12(3) (2020-03-01)
The objective of this study was to determine the effect of long-term (48 days), per os administration of specific zearalenone (ZEN) doses (20 and 40 μg ZEN/kg BW in experimental groups EI and EII, which were equivalent to 200% and
Toxigenic fungi and mycotoxins in the barley-to-beer chain
Brewing Microbiology, 107-139 (2015)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| Z0167-5MG | 04061837588464 |
| Z0167-1MG | 04061826236864 |