A0274
抗霉素A2
~90%
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关于此项目
经验公式（希尔记法）:
C27H38N2O9
化学文摘社编号:
分子量:
534.60
UNSPSC Code:
51101500
PubChem Substance ID:
EC Number:
248-342-1
MDL number:
InChI key
LYDAGTPXPZARPR-UHFFFAOYSA-N
InChI
1S/C27H38N2O9/c1-5-7-8-9-12-19-24(38-21(31)11-6-2)17(4)37-27(35)22(16(3)36-26(19)34)29-25(33)18-13-10-14-20(23(18)32)28-15-30/h10,13-17,19,22,24,32H,5-9,11-12H2,1-4H3,(H,28,30)(H,29,33)
SMILES string
CCCCCCC1C(OC(=O)CCC)C(C)OC(=O)C(NC(=O)c2cccc(NC=O)c2O)C(C)OC1=O
assay
~90%
antibiotic activity spectrum
fungi
mode of action
enzyme | inhibits
storage temp.
−20°C
General description
Chemical structure: peptide
Biochem/physiol Actions
Antimycin A2 is used to study ubiquinol (semiquinone/ubiquinone) oxidation/reduction, free radical generation, and the inhibition of cytochrome c oxidoreductase (mitochondrial complex III).
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
涉药品监管产品
此项目有
Jörgen Ådén et al.
Protein expression and purification, 172, 105628-105628 (2020-03-27)
Programmed cell death (apoptosis) is an essential mechanism in life that tightly regulates embryogenesis and removal of harmful cells. Besides an extrinsic pathway, an intrinsic (mitochondrial) apoptotic pathway exists where mitochondria are actively involved in cellular clearance in response to
Robin K Minor et al.
Scientific reports, 1, 70-70 (2012-02-23)
Sirt1 is an NAD(+)-dependent deacetylase that extends lifespan in lower organisms and improves metabolism and delays the onset of age-related diseases in mammals. Here we show that SRT1720, a synthetic compound that was identified for its ability to activate Sirt1
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