A0479
Adrafinil
≥98% (HPLC), solid
别名:
2-[(Diphenylmethyl)sulfinyl]acetohydroxamic acid, CRL 40028, Olmifon
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关于此项目
经验公式（希尔记法）:
C15H15NO3S
化学文摘社编号:
分子量:
289.35
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
264-303-1
MDL number:
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
color
white
solubility
DMSO: 35 mg/mL
SMILES string
ONC(=O)CS(=O)C(c1ccccc1)c2ccccc2
InChI
1S/C15H15NO3S/c17-14(16-18)11-20(19)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15,18H,11H2,(H,16,17)
InChI key
CGNMLOKEMNBUAI-UHFFFAOYSA-N
Biochem/physiol Actions
Agent promoting wakefulness; analog of Modafinil.
Disclaimer
Hygroscopic
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
C L Milhaud et al.
Journal de pharmacologie, 16(4), 372-380 (1985-10-01)
The nocturnal activity of a primate was used as an evaluation criterium for a stimulating substance: adrafinil (CRL 40028). Ten rhesus monkeys were placed in a controlled environment and their activity was measured, in relative time, using an ultra-sound system.
C T Siwak et al.
Progress in neuro-psychopharmacology & biological psychiatry, 24(5), 709-726 (2001-02-24)
1. Adrafmil is a novel vigilance promoting agent developed in France by Louis Lafon Laboratories. 2. Adrafinil causes increased locomotion without producing stereotypical activity in canines tested in an open field. 3. The effectiveness of a single treatment is long-lasting
C T Siwak et al.
American journal of veterinary research, 61(11), 1410-1414 (2000-12-07)
To compare the efficacy of adrafinil, propentofylline, and nicergoline for enhancing behavior of aged dogs. 36 Beagles between 9 and 16 years old. Dogs were randomly assigned to receive adrafinil (20 mg/kg of body weight, PO, q 24 h; n