A0770
Adenosine 5′-triphosphate 镁盐
95-98%
别名:
ATP 镁盐
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关于此项目
经验公式(希尔记法):
C10H16N5O13P3 · xMg2+
化学文摘社编号:
分子量:
507.18 (free acid basis)
MDL编号:
UNSPSC代码:
12352204
方案
95-98%
溶解性
H2O: 50 mg/mL
储存温度
−20°C
SMILES字符串
[Mg].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C3O
InChI
1S/C10H16N5O13P3.Mg.2H/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;
InChI key
CPGAIACWYFBIFN-UHFFFAOYSA-N
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生化/生理作用
P2 嘌呤能激动剂;增加 Ca2+-激活的 K+ 通道的活性;ATP-依赖酶系统的底物
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Daniela Cihalova et al.
Cancer chemotherapy and pharmacology, 76(1), 105-116 (2015-05-20)
ATP-binding cassette (ABC) transporters play an important role in multidrug resistance (MDR) toward anticancer drugs. Here, we evaluated interactions of cyclin-dependent kinase inhibitors (CDKi) AT-7519, flavopiridol and SNS-032 with the following ABC transporters in vitro: P-glycoprotein (ABCB1), breast cancer resistance
Sanna R Rijpma et al.
Malaria journal, 13, 359-359 (2014-09-15)
Therapeutic blood plasma concentrations of anti-malarial drugs are essential for successful treatment. Pharmacokinetics of pharmaceutical compounds are dependent of adsorption, distribution, metabolism, and excretion. ATP binding cassette (ABC) transport proteins are particularly involved in drug deposition, as they are located
Rebecca S Hofford et al.
Behavioural brain research, 270, 151-158 (2014-05-14)
Environmental factors influence a variety of health-related outcomes. In general, being raised in an environment possessing social, sensory, and motor enrichment reduces the rewarding effects of various drugs, thus protecting against abuse vulnerability. However, in the case of methamphetamine (METH)
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