Anti-AP-2α antibody produced in rabbit

Activation Protein transcription factor 2 (AP-2) is a developmentally modulated transcription factor that binds to specific sequence such as CCCCAGGC or related sequences. These sequences are usually present in several promoter and enhancer gene regions, including the promoters of the AP-2 genes themselves,,. AP-2 expression has also been linked to human breast cancer cells.
By immunoblotting, rabbit anti-AP-2α reacts specifically with human AP-2α. The sequence recognized by the antibody differs from the corresponding mouse sequence by one residue and from the chicken sequence by 2 residues.

synthetic peptide corresponding to human AP-2α, C-terminal sequence, (amino acids 420-437) conjugated to KLH with glutaraldehyde.

Rabbit anti-AP-2alpha antibody can be used for western blot (1:250), microarray and indirect immunofluorescence (1:100) assays.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

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