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Merck
CN

A1030

Sigma-Aldrich

Adenosine Deaminase from calf intestinal mucosa

Type VIII, ammonium sulfate suspension, ~200 units/mg protein

别名:

腺苷脱氨基酶

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类型

Type VIII

表单

ammonium sulfate suspension

比活

~200 units/mg protein

储存温度

2-8°C

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外形

Suspension in 3.2 M (NH4)2SO4, pH approx. 6

分析说明

Protein determined by biuret.

其他说明

One unit will deaminate 1.0 μmole of adenosine to inosine per min at pH 7.5 at 25 °C.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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分析证书(COA)

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Unveiling the binding mode of adenosine deaminase inhibitors to the active site of the enzyme: implication for rational drug design : presented by Maria P. Abbracchio.
Maria Letizia Trincavelli
Purinergic signalling, 9(1), 1-3 (2013-01-29)
Neutropenia and myeloid dysplasia in a patient with delayed-onset adenosine deaminase deficiency.
Keiko Nomura et al.
Pediatric blood & cancer, 60(5), 885-886 (2013-01-22)
Mary Carmen Pérez-Aguilar et al.
Investigacion clinica, 53(3), 315-324 (2012-12-20)
Adenosine deaminase is an enzyme of the purine metabolism whose function is to convert adenosine to inosine and deoxyadenosine to deoxyinosine. The ecto-ADA1 binding to the cell surface through CD26 contributes to the regulation of cytokines and stimulates the proliferation
Aamira Tariq et al.
Nucleic acids research, 41(4), 2581-2593 (2013-01-01)
RNA editing by adenosine deaminases that act on RNA (ADARs) diversifies the transcriptome by changing adenosines to inosines. In mammals, editing levels vary in different tissues, during development, and also in pathogenic conditions. From a screen for repressors of editing
Yeon-Mi Lee et al.
Biophysical chemistry, 172, 18-25 (2013-01-22)
Human ADAR1, which has two left-handed Z-DNA binding domains, preferentially binds Z-DNA rather than B-DNA with a high binding affinity. Z-DNA can be induced in long genomic DNA by Z-DNA binding proteins through the formation of two B-Z junctions with

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