A1471
A-85783
别名:
(R)-6-(4-Fluorophenyl)-N,N-dimethyl-3-[3-(3-pyridinyl)-1H,3H-pyrrolo[1,2-c]thiazol-7-yl]carbonyl-1H-indole-1-carboxamide
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选择尺寸
关于此项目
经验公式（希尔记法）:
C29H23FN4O2S
化学文摘社编号:
分子量:
510.58
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
form
solid
mp
185.3-186.5 °C (lit.)
solubility
DMSO: 13 mg/mL, H2O: insoluble
storage temp.
2-8°C
SMILES string
CN(C)C(=O)n1cc(C(=O)c2ccn3[C@H](SCc23)c4cccnc4)c5ccc(cc15)-c6ccc(F)cc6
InChI
1S/C29H23FN4O2S/c1-32(2)29(36)34-16-24(22-10-7-19(14-25(22)34)18-5-8-21(30)9-6-18)27(35)23-11-13-33-26(23)17-37-28(33)20-4-3-12-31-15-20/h3-16,28H,17H2,1-2H3/t28-/m1/s1
InChI key
YGUVFPOGHIKVPP-MUUNZHRXSA-N
General description
Shown to be effective both in vivo and in vitro. A-85783 is neutral and lipophilic and has been shown to competitively and reversibly inhibit [3H]PAF binding to rabbit platelet membranes as well as block PAF-induced serotonin release from rabbit platelets.
Biochem/physiol Actions
Potent and selective platelet-activating factor (PAF) receptor antagonist.
Features and Benefits
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Legal Information
Sold under license from Abbott Laboratories.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
相关内容
Datasheet
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