A2099
N-Acetyl-Leu-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin
≥95% (HPLC), solid
别名:
Ac-LEVD-AFC
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选择尺寸
关于此项目
经验公式（希尔记法）:
C32H40N5O11F3
分子量:
727.68
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
InChI key
FETZKXHXYOHAAN-LFYAFONDSA-N
SMILES string
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(OC(=O)C=C2C(F)(F)F)c1
InChI
1S/C32H40F3N5O11/c1-14(2)10-21(36-16(5)41)30(49)38-20(8-9-24(42)43)28(47)40-27(15(3)4)31(50)39-22(13-25(44)45)29(48)37-17-6-7-18-19(32(33,34)35)12-26(46)51-23(18)11-17/h6-7,11-12,14-15,20-22,27H,8-10,13H2,1-5H3,(H,36,41)(H,37,48)(H,38,49)(H,39,50)(H,40,47)(H,42,43)(H,44,45)/t20-,21-,22-,27-/m0/s1
assay
≥95% (HPLC)
form
solid
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
rat ... Prkcq(85420)
Biochem/physiol Actions
Fluorogenic substrate for caspase 4.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Ilona Domracheva et al.
Life sciences, 186, 92-101 (2017-08-16)
This study was designed to investigate the mechanism underlying cancer cell apoptosis caused by selenophenoquinolinones and coumarins. Twelve derivatives were studied according to their ability to suppress the proliferation of cancer cells in vitro (i.e., HepG2, MH-22A, MCF-7), induce cell
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