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Merck
CN

A2275

Sigma-Aldrich

[Sar1, Val5, Ala8]-血管紧张素 II 乙酸盐 水合物

≥97% (HPLC), powder

别名:

沙拉新

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关于此项目

经验公式（希尔记法）:
C42H65N13O10 · xC2H4O2 · yH2O
化学文摘社编号:
39698-78-7
分子量:
912.05 (anhydrous free base basis)
MDL编号:
MFCD01939339
UNSPSC代码:
12352202
PubChem化学物质编号:
24890641

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方案

≥97% (HPLC)

表单

powder

储存温度

−20°C

SMILES字符串

O.CC(O)=O.CNCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](C)C(O)=O

InChI

1S/C42H65N13O10.C2H4O2.H2O/c1-22(2)33(53-35(58)28(50-32(57)20-45-6)9-7-15-47-42(43)44)38(61)51-29(17-25-11-13-27(56)14-12-25)36(59)54-34(23(3)4)39(62)52-30(18-26-19-46-21-48-26)40(63)55-16-8-10-31(55)37(60)49-24(5)41(64)65;1-2(3)4;/h11-14,19,21-24,28-31,33-34,45,56H,7-10,15-18,20H2,1-6H3,(H,46,48)(H,49,60)(H,50,57)(H,51,61)(H,52,62)(H,53,58)(H,54,59)(H,64,65)(H4,43,44,47);1H3,(H,3,4);1H2/t24-,28-,29-,30-,31-,33-,34-;;/m0../s1

InChI key

YBZYNINTWCLDQA-UHKVWXOHSA-N

基因信息

human ... AGTR1(185)
rat ... Agtr1(24180)

Amino Acid Sequence

Sar-Arg-Val-Tyr-Val-His-Pro-Ala

生化/生理作用

竞争性血管紧张素 II 拮抗剂，抑制大鼠体内的血管紧张素 II 的升压效应，降低人体内血压。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
089K5063
057K5102
084K51063
084K5106
069H5801

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Cardiologia (Rome, Italy), 39(12 Suppl 1), 397-400 (1994-12-01)
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We determined the effects of losartan and CGP42112A (selective ligands of the AT1 and AT2 angiotensin receptors, respectively) and salarasin (a relatively nonselective angiotensin receptor antagonist) on urinary volume and urinary sodium and potassium excretion induced by administration of angiotensin
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