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Merck
CN

A2500

非那西丁

powder

别名:

N-(4-乙氧苯基)乙酰胺, 乙酰乙氧基苯胺, 乙酰对氨基苯乙醚, 对乙氧基乙酰苯胺, 对乙酰乙氧基苯胺

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关于此项目

线性分子式:
CH3CONHC6H4OC2H5
化学文摘社编号:
分子量:
179.22
EC Number:
200-533-0
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1869238
MDL number:
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InChI key

CPJSUEIXXCENMM-UHFFFAOYSA-N

InChI

1S/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12)

SMILES string

CCOc1ccc(NC(C)=O)cc1

form

powder

storage temp.

2-8°C

mp

133-136 °C

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Biochem/physiol Actions

CYP1A2 和 CYP2D6 的底物。

pictograms

Health hazardExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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分析证书(COA)

Lot/Batch Number

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Mojca Brunskole et al.
Bioorganic & medicinal chemistry, 16(11), 5881-5889 (2008-05-17)
Trihydroxynaphthalene reductase (3HNR) is an essential enzyme in the biosynthesis of fungal melanin and it represents an emerging target for the development of new fungicides and antimicotics. To promote the discovery of new inhibitors, an improved chemical synthesis of the
Huaping Mo et al.
Bioorganic & medicinal chemistry letters, 20(22), 6712-6715 (2010-09-25)
A simple and rapid NMR method is described to determine the logP of pharmaceutical agents. This method is highly versatile and efficient, because it does not require the use of deuterated solvents or the addition of any internal/external standards to
Stanislav Gobec et al.
Bioorganic & medicinal chemistry letters, 15(23), 5170-5175 (2005-09-27)
Nonsteroidal anti-inflammatory drugs (NSAIDs) like indomethacin, flufenamic acid, and related compounds have been recently identified as potent inhibitors of AKR1C3. We report that some other NSAIDs (diclofenac and naproxen) also inhibit AKR1C3, with the IC(50) values in the low micromolar
M Kummu et al.
Placenta, 36(10), 1185-1191 (2015-08-26)
Perfluorinated alkyl acids (PFAAs) are widely used in industry and consumer products. Pregnant women are exposed to PFAAs and their presence in umbilical cord blood represents fetal exposure. Interestingly, PFAAs are substrates for organic anion transporters (OAT) of which OAT4
Haiyan Li et al.
European journal of medicinal chemistry, 44(4), 1600-1606 (2008-09-05)
The first-principle, quantitative structure-hepatic clearance relationship for 50 drugs was constructed based on selected molecular descriptors calculated by TSAR software. The R(2) of the predicted and observed hepatic clearance for the training set (n=36) and test set (n=13) were 0.85

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