A2726
Anti-ADAM-10, C-terminal antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-A Disintegrin And Metalloproteinase-10, Anti-Kuzbanian, Anti-MADM
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
UNSPSC Code:
12352203
MDL number:
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, bovine, rat, human
technique(s)
western blot: 1:500-1:2,000
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... ADAM10(102)
General description
ADAM is a member of the A Distintegrin and Metalloproteinase family of proteins which possess both adhesion and zinc protease functions. ADAM-10 is a sheddase with both a secreted and membrane-bound form. ADAM-10 null mice are embryonically lethal with nural and cardiac defects.
In immunoblotting, an 80-85 kDa band can be detected, which may represent the precursor proform. A 60 kDa faint band may be detected in some cell lines including Jurkat, which appears to be the processed mature protein. Also, bands at below 50 kDa may be seen.
Immunogen
synthetic peptide corresponding to amino acids 732-748 of human ADAM-10. The sequence is identical to bovine and rat and differs by one amino acid in mouse.
Application
Rabbit anti-ADAM-10, C-terminal antibody can be used for immunoblotting assays at dilutions ranging from 1:500-1:2,000.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
存储类别
10 - Combustible liquids
法规信息
新产品
此项目有
相关内容
Instructions
Can Zhang et al.
The Journal of biological chemistry, 285(37), 28472-28480 (2010-07-14)
Alzheimer disease (AD) is a devastating neurodegenerative disease with no cure. The pathogenesis of AD is believed to be driven primarily by amyloid-beta (Abeta), the principal component of senile plaques. Abeta is an approximately 4-kDa peptide generated via cleavage of
Vedanta Mehta et al.
Arteriosclerosis, thrombosis, and vascular biology, 38(8), 1845-1858 (2018-06-09)
Objective- NRP1(neuropilin-1) acts as a coreceptor for VEGF (vascular endothelial growth factor) with an essential role in angiogenesis. Recent findings suggest that posttranslational proteolytic cleavage of VEGF receptors may be an important mechanism for regulating angiogenesis, but the role of
Martin Steuble et al.
Biology open, 1(8), 761-774 (2012-12-06)
Endocytosis of amyloid-β precursor protein (APP) is thought to represent the major source of substrate for the production of the amyloidogenic Aβ peptide by the β-secretase BACE1. The irreversible nature of proteolytic cleavage implies the existence of an efficient replenishment