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Merck
CN

A2851

Sigma-Aldrich

Anti-ADAM-10, Prohormone Convertase Activation Site antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

别名:

Anti-A Disintegrin And Metalloproteinase-10, Anti-Kuzbanian, Anti-MADM

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关于此项目

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous glycerol solution

种属反应性

human

浓度

~1 mg/mL

技术

western blot: 1:1,000

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... ADAM10(102)

一般描述

ADAM is a member of the disintegrin and metalloproteinase family of proteins which possess both adhesion and zinc protease functions. ADAM-10 is a sheddase with both a secreted and membrane-bound form. ADAM-10 null mice are embryonically lethal with neural and cardiac defects. Rabbit anti-ADAM-10 antibody can localize human ADAM 10 and does not detect other ADAMs.
Recognizes the furin cleavage site (58-60 kDa) of ADAM-10. Detects the latent form of the enzyme.

免疫原

synthetic peptide corresponding to the prohormone convertase (PC) cleavage site of human ADAM-10.

应用

Rabbit anti-ADAM-10 antibody has been used for western blot assays.

外形

Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hiroshi Tanahashi et al.
Neuroscience letters, 439(3), 293-297 (2008-06-07)
In a previous study, we reported that Alzheimer's disease-associated presenilin-2 interacts with a LIM-domain protein, namely, DRAL/FHL2/SLIM3. In this study, we investigated whether DRAL modifies the metabolism of the amyloid precursor protein (APP). We used small interfering RNA (siRNA) to
Ting Wang et al.
Phytotherapy research : PTR, 33(4), 1074-1083 (2019-02-16)
Osteoporosis is characterized by low bone mineral density and microarchitectural deterioration of bone tissue. N-(3-methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (MBOC) is one of the macamides isolated from Maca (Lepidium meyenii Walp.), a cruciferous plant from the Andes of Peru. In this study, C3H/10T1/2 mesenchymal
The ADAMs family of metalloproteases: multidomain proteins with multiple functions.
Darren F Seals et al.
Genes & development, 17(1), 7-30 (2003-01-07)

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