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Merck
CN

A3612

Ceftizoxime sodium salt

别名:

Ceftizoxime sodium

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关于此项目

线性分子式:
C13H12N5NaO5S2
化学文摘社编号:
分子量:
405.38
UNSPSC Code:
51284149
NACRES:
NA.85
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form

solid

color

white to faint yellow

solubility

DMSO: 1 mg/mL

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell wall synthesis | interferes

storage temp.

−20°C

InChI

1S/C13H13N5O5S2.Na/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18;/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22);/q;+1/p-1/b17-7-;/t8-,11-;/m1./s1

InChI key

ADLFUPFRVXCDMO-LIGXYSTNSA-M

Biochem/physiol Actions

Ceftizoxime is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.

Packaging

50mg

Other Notes

Keep container tightly closed in a dry and well-ventilated place.


signalword

Warning

pictograms

Exclamation mark

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Soraya Maria Zandim Maciel Dias Ferreira et al.
Bioorganic & medicinal chemistry letters, 22(14), 4605-4608 (2012-06-26)
Osteomyelitis is an infectious disease located in the bone or bone marrow. Long-circulating and pH-sensitive liposomes containing a technetium-99m-labeled antibiotic, ceftizoxime, (SpHL-(99m)Tc-CF) were developed to identify osteomyelitis foci. Biodistribution studies and scintigraphic images of bone infection or non infection-bearing rats
M Jayahar Bharathi et al.
Ophthalmic research, 47(1), 52-56 (2011-07-02)
To evaluate resistances mediated by extended-spectrum β-lactamases (ESBLs) and AmpC β-lactamases among Gram-negative bacteria recovered from ocular infections. As per the Clinical Laboratory Standards Institute M100-S-16 document, a total of 135 Gram-negative bacilli were recovered from ocular specimens and were
Bashier Osman et al.
BMC research notes, 6, 57-57 (2013-02-12)
A prophylactic antibiotic is recommended to reduce infection-related complication following cesarean delivery. There is a current debate on the time of prophylactic antibiotic in cesarean delivery. An opened randomized, controlled clinical trial was conducted at Soba hospital, Sudan to investigate



全球贸易项目编号

货号GTIN
A3612-50MG04061833361436