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Merck
CN

A3979

Sigma-Aldrich

Anti-Na+/K+ ATPase (β2-subunit) antibody produced in rabbit

whole antiserum, liquid

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MDL编号:
UNSPSC代码:
12352203
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生物来源

rabbit

偶联物

unconjugated

抗体形式

whole antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

表单

liquid

种属反应性

rat

技术

immunohistochemistry: 1:200
western blot: 1:1,000 using brain microsomal preparation

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

rat ... Atp1b2(24214)

一般描述

The Na+/K+ ATPase is an integral membrane enzyme that regulates ATP-dependent transport of Na+ and K+ across cell membranes. The Na+/K+ ATPase consists of a large, multipass, transmembrane catalytic α subunit, and an associated smaller β glycoprotein subunit. Studies indicate that there are three isoforms of the α subunit (α1, 2, and 3) and two isoforms of the β subunit (β1 and 2) encoded by two multigene families. Rabbit anti-Na+/K+ ATPase (β2-subunit) antibody is specific for the rat β2-subunit.

免疫原

β2 subunit fusion protein containing residues 63-285, as deduced from cDNA. The β2 subunit exhibits virtual identity with the glial cell adhesion molecule AMOG.

应用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Rabbit anti-Na+/K+ ATPase (β2-subunit) antibody can be used for western blot (1:1,000 using brain microsomal preparation) and immunohistochemistry (1:200) assays.

外形

The antibody is supplied as 200μL of whole antiserum

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Y Sun et al.
The American journal of physiology, 262(6 Pt 1), C1491-C1499 (1992-06-11)
While Western blot analysis clearly revealed the presence of the alpha- and beta-subunits of Na(+)-K(+)-ATPase in a variety of rat tissues, beta was not readily detectable in liver. This observation was consistent with a previous report indicating that Na(+)-K(+)-ATPase immunoprecipitated
A Mobasheri et al.
Cell biology international, 21(4), 201-212 (1997-04-01)
We have used isoform-specific antibodies against the Na+, K(+)-ATPase alpha (alpha 1, alpha 2 and alpha 3) and beta (beta 1 and beta 2) subunit isoforms in order to establish their specific localization in isolated bovine articular chondrocytes. Immunoblotting confirmed
Lylia Nini et al.
BMC biochemistry, 8, 18-18 (2007-09-21)
Heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins), composed of G alpha, G beta, and G gamma subunits, are positioned at the inner face of the plasma membrane and relay signals from activated G protein-coupled cell surface receptors to various signaling
Michał Biernacki et al.
Advances in medical sciences, 64(1), 15-23 (2018-09-23)
The effect of chronic administration of [3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate (URB597), inhibitor of fatty acid amide hydrolase (FAAH) that hydrolyzes anandamide, on cross-talk between endocannabinoid system, oxidative status and pro-inflammatory factors in the liver of spontaneously hypertensive rats (SHRs) was investigated. Experiments

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