A4604
Anti-α1C Adrenergic Receptor antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
availability
not available in Japan
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 2 μg/mL using prostate, glandular epithelium
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Quality Level
Gene Information
human ... ADRA1A(148)
General description
Adrenergic receptors (ARs) belong to the G protein-coupled receptor superfamily that interacts with epinephrine and norepinephrine. There are nine receptor subtypes which include three α1AR subtypes (α1A/D, α1B, and α1C), three α2ARs (α2A, α2B, and α2C), and three βAR subtypes (β1, β2, and β3). Adrenergic receptors have been implicated in many diseases such as hypertension, glaucoma, cardiac disorders, diabetes, impotence and depression. Rabbit Anti-α1C Adrenergic Receptor antibody specifically recognizes human α1C adrenergic receptor.
Immunogen
synthetic peptide corresponding to the third cytoplasmic loop of human α1C adrenergic receptor. The immunizing peptide has 100% homology with the rat and mouse gene.
Application
Rabbit Anti-α1C Adrenergic Receptor can be used for immunohistochemistry at 2μg/mL using prostate and glandular epithelial tissues.
Physical form
Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Jing Xue et al.
Cell reports, 28(11), 2892-2904 (2019-09-12)
Cyclin-dependent kinases (CDKs) contribute to vital cellular processes including cell cycle regulation. Loss of CDKs is associated with impaired insulin secretion and β cell survival; however, the function of CDK8 in β cells remains elusive. Here, we report that genetic
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