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Merck
CN

A4604

Anti-α1C Adrenergic Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p)
Citations:
1
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

availability

not available in Japan

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 2 μg/mL using prostate, glandular epithelium

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... ADRA1A(148)

General description

Adrenergic receptors (ARs) belong to the G protein-coupled receptor superfamily that interacts with epinephrine and norepinephrine. There are nine receptor subtypes which include three α1AR subtypes (α1A/D, α1B, and α1C), three α2ARs (α2A, α2B, and α2C), and three βAR subtypes (β1, β2, and β3). Adrenergic receptors have been implicated in many diseases such as hypertension, glaucoma, cardiac disorders, diabetes, impotence and depression. Rabbit Anti-α1C Adrenergic Receptor antibody specifically recognizes human α1C adrenergic receptor.

Immunogen

synthetic peptide corresponding to the third cytoplasmic loop of human α1C adrenergic receptor. The immunizing peptide has 100% homology with the rat and mouse gene.

Application

Rabbit Anti-α1C Adrenergic Receptor can be used for immunohistochemistry at 2μg/mL using prostate and glandular epithelial tissues.

Physical form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.


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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Jing Xue et al.
Cell reports, 28(11), 2892-2904 (2019-09-12)
Cyclin-dependent kinases (CDKs) contribute to vital cellular processes including cell cycle regulation. Loss of CDKs is associated with impaired insulin secretion and β cell survival; however, the function of CDK8 in β cells remains elusive. Here, we report that genetic



全球贸易项目编号

货号GTIN
A4604-50UL04061835805150