A4730
Amthamine dihydrobromide
≥98% (HPLC), solid
别名:
2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide
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经验公式（希尔记法）:
C6H11N3S · 2HBr
化学文摘社编号:
分子量:
319.06
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
assay
≥98% (HPLC)
form
solid
color
off-white
solubility
H2O: 27 mg/mL
storage temp.
2-8°C
SMILES string
Br[H].Br[H].Cc1nc(N)sc1CCN
InChI
1S/C6H11N3S.2BrH/c1-4-5(2-3-7)10-6(8)9-4;;/h2-3,7H2,1H3,(H2,8,9);2*1H
InChI key
XFXNNOPUDSFVJE-UHFFFAOYSA-N
Application
Amthamine dihydrobromide is a histamine H2 receptor agonist. Amthamine dihydrobromide has been used to study the effect of mast cells on T regulatory cell function.
Biochem/physiol Actions
Amthamine dihydrobromide is a H2 histamine receptor agonist. Amthamine dihydrobromide, similar to histamine, inhibits H2 receptor-mediated eosinophil peroxidase (EPO) release with IC50 = 0.4 μM; a weak antagonist at H3 and shows no activity at H1 receptors.
H2 histamine receptor agonist.
存储类别
13 - Non Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable