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Merck
CN

A4845

Monoclonal Anti-Alx-4 antibody produced in mouse

clone KABB4, purified immunoglobulin, buffered aqueous solution

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
KABB4, monoclonal
Application:
WB
Citations:
3
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

KABB4, monoclonal

form

buffered aqueous solution

mol wt

antigen 41-43 kDa

species reactivity

human

technique(s)

western blot: 1-5 μg/mL

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ALX4(60529)

General description

Axl-4 is a homeodomain protein that is expressed on a variety of tissues including osteoblast precursors, dermal papilla of hair and whisker follicles, dental papilla of teeth, and mesenchymal cells. This protein functions as a transcriptional activator at epithelial-mesenchymal interfaces. Mouse Monoclonal Anti-Alx-4 antibody binds to human AXL-4.

Immunogen

recombinant full length Alx-4.

Application

Mouse Monoclonal Anti-Alx-4 antibody has been used for western blot analysis.

Physical form

Solution at approximately 1 mg/ml in 0.01 M phosphate buffered saline, pH 7.4, containing 0.08% sodium azide.

Preparation Note

Purified using protein G.


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相关内容


S Qu et al.
Gene, 203(2), 217-223 (1998-01-13)
Homeodomain containing transcription factors serve important functions in patterning the embryo during vertebrate development. We have isolated cDNA clones encoding a novel protein, named Alx-4, that contains a paired-type homeodomain. Analysis of the homeodomain sequence shows that Alx-4 belongs to
Julie A Gaasch et al.
Gene, 369, 142-152 (2006-01-13)
Hepatocyte Growth Factor (HGF) and its protooncogene receptor c-Met regulate osteoclast function by activating pp60(c-Src) kinase and alpha(v)beta3 integrin. HGF causes transcription yet in osteoclast cells, this gene regulation is currently unknown. To begin characterization of HGF-regulated gene expression in
R Hudson et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 213(2), 159-169 (1998-10-24)
We have recently demonstrated that the retinoblastoma family of negative cell cycle regulators can form complexes with a class of developmental factors which contain paired-like (PL) homeodomains (Wiggan et al. [1998] Oncogene 16:227-236). Our screens led to the isolation of



全球贸易项目编号

货号GTIN
A4845-.1MG04061836275402