A4887
天门冬酰胺酶 来源于大肠杆菌
Grade V, buffered aqueous glycerol solution, ≥80 units/mg protein
别名:
L -天冬酰胺酰胺水解酶
类型
Grade V
表单
buffered aqueous glycerol solution
比活
≥80 units/mg protein
储存温度
2-8°C
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外形
Solution in 50% glycerol, pH 6.5
分析说明
Protein determined by biuret.
其他说明
One unit will liberate 1.0 μmole of ammonia from L-asparagine per min at pH 8.6 at 37 °C.
法规信息
新产品
此项目有
Wing H Tong et al.
Pediatric blood & cancer, 60(2), 258-261 (2012-09-11)
Mesenchymal cells (MSCs) in bone marrow (BM) may produce asparagine and form protective niches for leukemic cells. In vitro, this led to high levels of asparagine and conferred asparaginase resistance to acute lymphoblastic leukemia (ALL) cells. The aim of this
Marieta Anton-Harisi et al.
Journal of pediatric hematology/oncology, 34(8), e337-e340 (2012-09-18)
We describe 2 patients, a 4-month-old male and a 17-month-old female, with de novo acute megakaryoblastic leukemia with increased number of hematogones at diagnosis. Both children were admitted in the hospital with thrombocytopenia. The bone marrow smears in the first
Lynda M Vrooman et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(9), 1202-1210 (2013-01-30)
We assessed the toxicity and efficacy of dexamethasone and a novel dosing method of Escherichia coli L-asparaginase (EC-Asnase) in children and adolescents with newly diagnosed acute lymphoblastic leukemia (ALL). Patients achieving complete remission (CR) on Dana-Farber Cancer Institute ALL Consortium
Jassada Buaboonnam et al.
Pediatric blood & cancer, 60(7), 1161-1164 (2013-01-22)
The efficacy of combination chemotherapy with methotrexate (MTX) and asparaginase is not well known in relapsed and refractory acute leukemia after contemporary therapy. A retrospective study of pediatric patients with relapsed or refractory acute myeloid leukemia (AML) who received MTX
E Truelove et al.
Leukemia, 27(3), 553-559 (2012-10-27)
The dramatic improvements seen in the outcome of paediatric patients with acute lymphoblastic leukaemia (ALL) have led to increasing incorporation of L-asparaginase (L-Asp) in adult treatment protocols. However, its use is associated with a disruption in the physiological balance between
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