A5284
8-氮鸟嘌呤
Hybri-Max™, γ-irradiated, powder, BioXtra, suitable for hybridoma
别名:
8-AzaG, 2-氨基-6-氧-8-氮杂嘌呤, 2-氨基-6-羟基-8-氮杂嘌呤, 癌散
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关于此项目
经验公式（希尔记法）:
C4H4N6O
化学文摘社编号:
分子量:
152.11
Beilstein:
171098
EC 号:
MDL编号:
UNSPSC代码:
12352207
PubChem化学物质编号:
等级
Hybri-Max™
无菌性
γ-irradiated
产品线
BioXtra
表单
powder
技术
cell culture | hybridoma: suitable
mp
>300 °C (lit.)
储存温度
−20°C
SMILES字符串
NC1=Nc2[nH]nnc2C(=O)N1
InChI
1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)
InChI key
LPXQRXLUHJKZIE-UHFFFAOYSA-N
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应用
用作杂交瘤细胞培养应用中的骨髓瘤选择剂。
制备说明
10mL 无菌细胞培养基可复原一小瓶本品。储备液足以制备 500mL 培养基。10mg/瓶包装的最终工作浓度：130μM 8-氮鸟嘌呤。分析证书上提供了每瓶的含量。
法律信息
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
July Fong et al.
Scientific reports, 8(1), 1155-1155 (2018-01-20)
The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence factors and formation of drug-resistant biofilms. Targeting
T L Bowen et al.
Journal of bacteriology, 178(9), 2521-2526 (1996-05-01)
Phosphoribosyltransferase (PRTase) and nucleoside phosphorylase (NPase) activities were detected by radiometric methods in extracts of Methanococcus voltae. Guanine PRTase activity was present at 2.7 nmol min(-1) mg of protein(-1) and had an apparent Km for guanine of 0.2 mM and
Sunirmal Paul et al.
Environmental and molecular mutagenesis, 47(5), 311-319 (2006-03-07)
Endogenous DNA damage clusters--two or more oxidized bases, abasic sites, or strand breaks within about 20 base pairs on opposing strands--can accumulate in unirradiated mammalian cells, and may be significant origins of spontaneous detrimental biological effects. Factors determining the levels
Erwan Atcheson et al.
NPJ vaccines, 5, 92-92 (2020-10-22)
Malaria remains one of the world's most urgent global health problems, with almost half a million deaths and hundreds of millions of clinical cases each year. Existing interventions by themselves will not be enough to tackle infection in high-transmission areas.
Qiao-Ling Gong et al.
Journal of molecular modeling, 18(2), 493-500 (2011-05-05)
The interaction between 8-azaguanine (8-Azan) and bovine serum albumin (BSA) in Tris-HCl buffer solutions at pH 7.4 was investigated by means of fluorescence and ultraviolet-visible (UV-Vis) spectroscopy. At 298 K and 310 K, at a wavelength of excitation (λ (ex))
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