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Merck
CN

A5284

8-氮鸟嘌呤

Hybri-Max, γ-irradiated, powder, BioXtra, suitable for hybridoma

别名:

8-AzaG, 2-氨基-6-氧-8-氮杂嘌呤, 2-氨基-6-羟基-8-氮杂嘌呤, 癌散

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关于此项目

经验公式(希尔记法):
C4H4N6O
化学文摘社编号:
分子量:
152.11
EC Number:
205-148-1
UNSPSC Code:
12352207
PubChem Substance ID:
Beilstein/REAXYS Number:
171098
MDL number:
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InChI

1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)

InChI key

LPXQRXLUHJKZIE-UHFFFAOYSA-N

SMILES string

NC1=Nc2[nH]nnc2C(=O)N1

grade

Hybri-Max

sterility

γ-irradiated

product line

BioXtra

form

powder

technique(s)

cell culture | hybridoma: suitable

mp

>300 °C (lit.)

storage temp.

−20°C

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Application

用作杂交瘤细胞培养应用中的骨髓瘤选择剂。

Preparation Note

10mL 无菌细胞培养基可复原一小瓶本品。储备液足以制备 500mL 培养基。10mg/瓶包装的最终工作浓度:130μM 8-氮鸟嘌呤。分析证书上提供了每瓶的含量。

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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July Fong et al.
Scientific reports, 8(1), 1155-1155 (2018-01-20)
The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence factors and formation of drug-resistant biofilms. Targeting
Qiao-Ling Gong et al.
Journal of molecular modeling, 18(2), 493-500 (2011-05-05)
The interaction between 8-azaguanine (8-Azan) and bovine serum albumin (BSA) in Tris-HCl buffer solutions at pH 7.4 was investigated by means of fluorescence and ultraviolet-visible (UV-Vis) spectroscopy. At 298 K and 310 K, at a wavelength of excitation (λ (ex))
Erwan Atcheson et al.
NPJ vaccines, 5, 92-92 (2020-10-22)
Malaria remains one of the world's most urgent global health problems, with almost half a million deaths and hundreds of millions of clinical cases each year. Existing interventions by themselves will not be enough to tackle infection in high-transmission areas.
Bashir Mir et al.
Nucleic acids research, 32(3), e25-e25 (2004-02-13)
The use of primary somatic cells in nuclear transfer procedure has opened a new opportunity to manipulate domestic animal genomes via homologous recombination. To date, while a few loci have been targeted in somatic cells using similar enrichment strategies as
Ziwei Li et al.
International journal of oncology, 52(6), 2079-2092 (2018-04-06)
Hepatocellular carcinoma (HCC) is one of the most common malignancies and causes of death worldwide. Research investigating novel therapeutic strategies for the treatment of HCC is urgently required. Monoclonal antibodies (mAbs) that target the programmed cell death‑1 (PD‑1/PDCD1)/programmed death-ligand 1

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