A5581
3,3-双(氨乙基)-1-羟基-2-氧代-1-三氮烯
≥95%
别名:
2,2′-(羟基亚硝基肼基)双乙胺, 3,3-二(氨乙基)-1-羟基-2-羰基-1-三氮烯, DETA NONOate
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关于此项目
经验公式(希尔记法):
C4H13N5O2
化学文摘社编号:
分子量:
163.18
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥95%
表单
powder
溶解性
0.1 M NaOH: 10 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
NCCN(CCN)\[N+]([O-])=N/O
InChI
1S/C4H13N5O2/c5-1-3-8(4-2-6)9(11)7-10/h10H,1-6H2/b9-7+
InChI key
YNRCBOXEDICOIX-VQHVLOKHSA-N
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应用
3,3-双(氨基乙基)-1-羟基-2-氧代-1-三氮烯已被用作神经元培养的一氧化氮供体补充剂。它也已用作一氧化氮供体,以研究亚硝酸盐处理后蛋白S-亚硝化(SNO)的作用。
已使用3,3-双(氨基乙基)-1-羟基-2-氧代-1-三氮烯深入了解可能有助于尼可地尔在心血管系统中产生有益作用的分子途径。 3,3-双(氨基乙基)-1-羟基-2-氧代-1-三氮烯以速率控制的方式自发释放一氧化氮。
生化/生理作用
3,3-双(氨基乙基)-1-羟基-2-氧代-1-三氮烯是长效一氧化氮供体。它可能在大鼠中表现出伤害性作用。
警示用语:
Danger
危险声明
危险分类
Self-react. C
储存分类代码
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
监管及禁止进口产品
此项目有
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一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。
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