产品名称
肾上腺色素, ≥95% (HPLC)
Quality Level
assay
≥95% (HPLC)
form
powder
color
red to brown
εmax
3-4.5 at 485-490 nm in water, 9.0-10.5 at 299-304 nm in water
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
SMILES string
CN1CC(O)C2=CC(=O)C(=O)C=C12
InChI
1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3
InChI key
RPHLQSHHTJORHI-UHFFFAOYSA-N
Application
肾上腺色素已被用于研究其对大鼠心脏冠状动脉收缩的影响。
Biochem/physiol Actions
肾上腺色素是肾上腺素的氧化产物。它与心脏毒性有关。它是一种短寿命的细胞毒性分子，是用于杀死细菌的白细胞反应的一部分。肾上腺色素也被建议用以获得拟精神病作用。它可用于确定超氧化物歧化酶的活性。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Viviana S Fluxá et al.
Nature protocols, 3(8), 1270-1277 (2008-08-21)
The adrenaline test for enzymes is a colorimetric enzyme assay based on the quantification of periodate-sensitive reaction products such as 1,2-diols and 1,2-aminoalcohols by back-titration of the oxidant with adrenaline to produce adrenochrome as an easily detectable red product. The
Adrenochrome-induced coronary artery constriction in the rat heart.
Karmazyn M, et al.
Journal of Pharmacology and Experimental Therapeutics, 219, 225-225 (1981)
Maria Luisa Genova et al.
Archives of biochemistry and biophysics, 447(2), 167-173 (2006-02-21)
Complex I in bovine heart submitochondrial particles catalyses the NADH-supported generation of superoxide anion; adrenaline is oxidised by superoxide to adrenochrome that, on its hand, is reduced by Complex I, thus establishing a redox cycle that amplifies the superoxide production.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A5752-25MG | 04061832339986 |
| A5752-250MG | 04061832339979 |