A6477
Anti-ADAMTS-3, C-Terminal antibody produced in rabbit
~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution
别名:
Anti-A Disintegrin And Metalloproteinase with ThromboSpondin-3 motif
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous glycerol solution
种属反应性
human
浓度
~1 mg/mL
技术
western blot: 1:1,000
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... ADAMTS3(9508)
一般描述
ADAMTS-3 belongs to the ADAM (A Disintegrin And Metalloproteinase) family and has thrombospondin (TS) repeats. Studies have suggested that ADAMTS-3 is preferably expressed in the cartilages and has procollagen II N-propeptidase functions. Rabbit Anti-ADAMTS-3, C-Terminal antibody binds to the C-terminus of human ADAMTS-3.
By immunoblotting against the reduced protein, the antibody identifies the zymogen form at 130-140 kDa, activated forms at 94-105 kDa (major bands), and breakdown products at 50 kDa, 34 kDa in cell culture media and lysates.
免疫原
synthetic peptide corresponding to the C-terminus of human ADAMTS-3.
应用
Rabbit Anti-ADAMTS-3, C-Terminal antibody can be used for western blot applications at a dilution of 1:1,000.
外形
Solution in phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
R J Fernandes et al.
The Journal of biological chemistry, 276(34), 31502-31509 (2001-06-16)
The amino and carboxyl propeptides of procollagens I and II are removed by specific enzymes as a prerequisite for fibril assembly. Null mutations in procollagen I N-propeptidase (ADAMTS-2) cause dermatosparaxis in cattle and the Ehlers-Danlos syndrome (dermatosparactic type) in humans
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