A6727
Anti-ADAMTS-5, C-Terminal antibody produced in rabbit
~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution
别名:
Anti-A Disintegrin And Metalloproteinase with ThromboSpondin-5 motif, Anti-Aggrecanase-2, Anti-Implantin
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关于此项目
UNSPSC Code:
12352203
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
species reactivity
human
concentration
~1 mg/mL
technique(s)
western blot: 1:1,000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ADAMTS5(11096)
General description
ADAMT5 is a member of the family of ADAMTs proteins that contain 3 specific domains: MMP, disintegrin, and a thrombospondin type-1 domain. ADAMT5 is highly expressed in cartilage.
By immunoblotting against the reduced protein, the antibody identifies the zymogen form at 120 kDa, activated form at 73 kDa (major band), and breakdown products at 50 kDa and 40 kDa in cell lysates.
Rabbit Anti-ADAMTS-5, C-terminal antibody binds to the C-terminus of human ADAMTS-5.
Immunogen
synthetic peptide corresponding to the C-terminus of human ADAMTS-5.
Application
Rabbit Anti-ADAMTS-5, C-Terminal antibody can be used for western blot applications at a dilution of 1:1,000.
Physical form
Solution in phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.
Hurskainen, T
Journal of Biochemistry, 274, 25555-25563 (1999)
Q Zhang et al.
Osteoarthritis and cartilage, 23(12), 2259-2268 (2015-07-15)
To identify whether cartilage master regulator SRY-related protein 9 (SOX9) mediates A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) dysregulation during osteoarthritis (OA) cartilage degeneration. Twenty-two randomly selected OA patients were evaluated using Outerbridge Classification via arthroscopy. Haematoxylin-eosin (HE), Safranin
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