A6727
Anti-ADAMTS-5, C-Terminal antibody produced in rabbit
~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution
别名:
Anti-A Disintegrin And Metalloproteinase with ThromboSpondin-5 motif, Anti-Aggrecanase-2, Anti-Implantin
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous glycerol solution
种属反应性
human
浓度
~1 mg/mL
技术
western blot: 1:1,000
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ADAMTS5(11096)
一般描述
ADAMT5 is a member of the family of ADAMTs proteins that contain 3 specific domains: MMP, disintegrin, and a thrombospondin type-1 domain. ADAMT5 is highly expressed in cartilage.
By immunoblotting against the reduced protein, the antibody identifies the zymogen form at 120 kDa, activated form at 73 kDa (major band), and breakdown products at 50 kDa and 40 kDa in cell lysates.
Rabbit Anti-ADAMTS-5, C-terminal antibody binds to the C-terminus of human ADAMTS-5.
免疫原
synthetic peptide corresponding to the C-terminus of human ADAMTS-5.
应用
Rabbit Anti-ADAMTS-5, C-Terminal antibody can be used for western blot applications at a dilution of 1:1,000.
外形
Solution in phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.
Hurskainen, T
Journal of Biochemistry, 274, 25555-25563 (1999)
Q Zhang et al.
Osteoarthritis and cartilage, 23(12), 2259-2268 (2015-07-15)
To identify whether cartilage master regulator SRY-related protein 9 (SOX9) mediates A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) dysregulation during osteoarthritis (OA) cartilage degeneration. Twenty-two randomly selected OA patients were evaluated using Outerbridge Classification via arthroscopy. Haematoxylin-eosin (HE), Safranin
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