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Merck
CN

A6950

Acetyl-Lys-D-Ala-D-Ala

≥95% (HPLC), powder

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关于此项目

经验公式(希尔记法):
C14H26N4O5
化学文摘社编号:
分子量:
330.38
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
MDL number:
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产品名称

Acetyl-Lys-D-Ala-D-Ala, ≥95% (HPLC)

SMILES string

CC(NC(=O)C(C)NC(=O)C(CCCCN)NC(C)=O)C(O)=O

InChI

1S/C14H26N4O5/c1-8(12(20)17-9(2)14(22)23)16-13(21)11(18-10(3)19)6-4-5-7-15/h8-9,11H,4-7,15H2,1-3H3,(H,16,21)(H,17,20)(H,18,19)(H,22,23)

InChI key

GMSXMADYKTYBCP-UHFFFAOYSA-N

assay

≥95% (HPLC)

form

powder

solubility

water: 10 mg/mL, clear, colorless

storage temp.

−20°C

Quality Level

General description

Substrate for carboxypeptidase G and DD from Streptomyces albus.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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P Groves et al.
Structure (London, England : 1993), 2(8), 747-754 (1994-08-15)
Glycopeptide antibiotics of the vancomycin group are of crucial clinical importance in the treatment of methicillin resistant Staphylococcus aureus (MRSA)--the often lethal 'super-bug'--characterized by its resistance to a wide range of antibiotics in common use. The antibiotics exert their physiological
D H Williams et al.
Science (New York, N.Y.), 280(5364), 711-714 (1998-05-23)
The cooperativity between binding of cell wall precursor analogs (ligands) to and antibiotic dimerization of the clinically important vancomycin group antibiotics was investigated by nuclear magnetic resonance. When dimerization was weak in the absence of a ligand, the increase in
L Varetto et al.
European journal of biochemistry, 162(3), 525-531 (1987-02-02)
Titration of the active-site serine DD-peptidase of Streptomyces R61 shows that formation of acyl enzyme during hydrolysis of the substrate Ac2-L-Lys-D-Ala-D-Ala and enzyme inactivation by the beta-lactam compounds benzylpenicillin, N-acetylampicillin and ampicillin relies on the acidic form of an enzyme's
Eric C DiBiasio et al.
Journal of bacteriology, 202(20) (2020-08-12)
Uropathogenic Escherichia coli (UPEC) is the leading cause of human urinary tract infections (UTIs), and many patients experience recurrent infection after successful antibiotic treatment. The source of recurrent infections may be persistent bacterial reservoirs in vivo that are in a

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