表单
powder
溶解性
alcohol: soluble
储存温度
2-8°C
SMILES字符串
CC(=O)NCCc1c[nH]c2ccccc12
InChI
1S/C12H14N2O/c1-9(15)13-7-6-10-8-14-12-5-3-2-4-11(10)12/h2-5,8,14H,6-7H2,1H3,(H,13,15)
InChI key
NVUGEQAEQJTCIX-UHFFFAOYSA-N
基因信息
human ... MTNR1A(4543), MTNR1B(4544)
一般描述
N-Acetyltryptamine is a melatonin analog present in mammalian blood. It is derived from tryptophan.
应用
N-Acetyltryptamine has been used as an internal standard in liquid chromatography-tandem mass spectrometry (LC/MS/MS). It has also been used as an internal standard in melatonin concentration assay and tandem mass spectrometry for the quantification of plasma melatonin levels.
生化/生理作用
Mixed agonist-antagonist at melatonin receptors; antioxidant.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
Burkhard Poeggeler et al.
Journal of pineal research, 33(1), 20-30 (2002-07-18)
Melatonin's O-methyl and N-acetyl residues are not only the basis of its amphilicity enabling the molecule to enter all organs and all subcellular compartments, but are also decisive for its antioxidant properties. We have compared melatonin's redox chemistry with that
Sameer Gupta et al.
General and comparative endocrinology, 239, 40-49 (2015-12-25)
The effect of photo-neuroendocrine system on the thymic (immune) functions is mediated by gonadal steroid and the pineal hormone melatonin. The present study explored the effect of photoperiod on the thymic melatonergic system and its role in protection of thymic
Sangkyu Park et al.
Journal of pineal research, 52(2), 211-216 (2011-09-03)
Melatonin biosynthesis was examined in Sekiguchi mutant rice lacking functional tryptamine 5-hydroxylase (T5H) activity, which is the terminal enzyme for serotonin biosynthesis in rice. During senescence process, the leaves of Sekiguchi mutant rice produced more tryptamine and N-acetyltryptamine compared with
C Kopp et al.
Neuropharmacology, 39(10), 1865-1871 (2000-07-08)
The anxiolytic-like properties of melatonin have been established in rodents. The present study investigated the possible involvement of melatonin receptors/binding sites in the regulation of emotional responsiveness in mice, using an mt1/MT2 receptor specific agonist (S 23478) and two specific
An-Qi Wang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(23), 2259-2264 (2011-07-06)
For the endogenous substances with an ultra-low level in biological fluids, such as melatonin, the blank biological matrix is obviously not "blank". This problem leads to a serious issue of the bioanalytical methods development and validation by liquid chromatography coupled
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