InChI
1S/C16H22N4O10/c1-7(21)26-6-11-14(27-8(2)22)15(28-9(3)23)13(16(30-11)29-10(4)24)19-12(25)5-18-20-17/h11,13-16H,5-6H2,1-4H3,(H,19,25)/t11-,13-,14+,15-,16?/m1/s1
SMILES string
O=C(C)O[C@H]1[C@@H](COC(C)=O)OC(OC(C)=O)[C@H](NC(CN=[N+]=[N-])=O)[C@H]1OC(C)=O
InChI key
HGMISDAXLUIXKM-YJUJGKJLSA-N
storage temp.
2-8°C
Application
非天然叠氮基糖，可以代谢方式引入模式生物，随后并入到聚糖结构。叠氮基可与结合到试剂的膦反应，用于可视化或选择性捕获。与 FLAG®-Phosphine™ (GPHOS1) 结合使用，与其他许多 FLAG 工具在两种应用下都兼容。
Legal Information
FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Qiang Zhu et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(14), 7755-7763 (2020-03-21)
Methionine metabolism is critical for the maintenance of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) pluripotency. However, little is known about the regulation of the methionine cycle to sustain ESC pluripotency. Here, we show that adenosylhomocysteinase (AHCY)
Malin E V Johansson
PloS one, 7(7), e41009-e41009 (2012-07-21)
The enormous bacterial load and mechanical forces in colon create a special requirement for protection of the epithelium. In the distal colon, this problem is largely solved by separation of the bacteria from the epithelium by a firmly attached inner
Boya Deng et al.
Neoplasia (New York, N.Y.), 20(10), 1038-1044 (2018-09-13)
Alteration of protein O-glycosylation in various human cancers including breast cancer is well known, but molecular roles of their aberrant glycosylations on cancer have not been fully understood. We previously reported critical roles of polypeptide N-acetylgalactosaminyltransferase 6 (GALNT6 or GalNAc-T6)
Anh Tuan Nguyen et al.
Cancer cell, 32(5), 639-653 (2017-11-15)
Cancers grow within tissues through molecular mechanisms still unclear. Invasiveness correlates with perturbed O-glycosylation, a covalent modification of cell-surface proteins. Here, we show that, in human and mouse liver cancers, initiation of O-glycosylation by the GALNT glycosyl-transferases increases and shifts
Julia E Maxson et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 22(3), 757-764 (2015-10-18)
Colony-stimulating factor 3 receptor (CSF3R) mutations have been identified in the majority of chronic neutrophilic leukemia (CNL) and a smaller percentage of atypical chronic myeloid leukemia (aCML) cases. Although CSF3R point mutations (e.g., T618I) are emerging as key players in
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