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Merck
CN

A7708

β-N-Acetylhexosaminidase from Aspergillus oryzae

lyophilized powder, ≥10 units/mg protein (Lowry)

别名:

β-N-Acetyl-D-hexosaminide N-acetyl-hexosaminohydrolase

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化学文摘社编号:
UNSPSC Code:
12352204
MDL number:
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form

lyophilized powder

specific activity

≥10 units/mg protein (Lowry)

composition

Protein, ~10% Lowry

storage temp.

2-8°C

Application

Stable biotransformation catalyst, for the synthesis of oligosaccharides.

Biochem/physiol Actions

Active on N-acetyl-β-D-glucosaminides and N-acetyl-β-D-galactosaminides.

Physical form

Contains MES buffer salts and EDTA

Other Notes

One unit will hydrolyze 1.0 μmole of p-nitrophenyl N-acetyl-β-D-glucosaminide to p-nitrophenol and N-acetyl-D-glucosamine per min at pH 5.0 at 30 °C.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

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Singh, S., et al.
Chemical Communications (Cambridge, England), 993-993 (1996)
Singh, S., et al.
Journal of the Chemical Society. Chemical Communications, 2227-2227 (1994)
Federica Vernuccio et al.
Recenti progressi in medicina, 103(12), 559-563 (2012-12-22)
Cardiorenal syndrome is a pathophysiological heart and kidney disorder, in which acute or chronic dysfunction of one organ induces a damage in the other. It's a syndrome more and more often encountered in clinical practice and this implies the need
David J Vocadlo
Current opinion in chemical biology, 16(5-6), 488-497 (2012-11-14)
The addition of N-acetylglucosamine (GlcNAc) O-linked to serine and threonine residues of proteins is known as O-GlcNAc. This post-translational modification is found within multicellular eukaryotes on hundreds of nuclear and cytoplasmic proteins. O-GlcNAc transferase (OGT) installs O-GlcNAc onto target proteins
Tyler Mark Pierson et al.
Molecular genetics and metabolism, 108(1), 65-69 (2012-11-20)
A 12 year-old female presented with a seven-year history of progressive muscle weakness, atrophy, tremor and fasciculations. Cognition was normal. Rectal biopsy revealed intracellular storage material and biochemical testing indicated low hexosaminidase activity consistent with juvenile-onset G(M2)-gangliosidosis. Genetic evaluation revealed

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