方案
≥98%
mp
199 °C (dec.) (lit.)
储存温度
−20°C
SMILES字符串
CC(=O)NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
InChI
1S/C11H15N3O6/c1-5(16)12-7-2-3-14(11(19)13-7)10-9(18)8(17)6(4-15)20-10/h2-3,6,8-10,15,17-18H,4H2,1H3,(H,12,13,16,19)/t6-,8-,9-,10-/m1/s1
InChI key
NIDVTARKFBZMOT-PEBGCTIMSA-N
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G Kawai et al.
Nucleic acids symposium series, (21)(21), 61-62 (1989-01-01)
The conformational characteristics of a modified nucleoside 4-acetylcytidine (ac4C) was analyzed by proton nuclear magnetic resonance spectroscopy. This nucleoside was found to take the C3'-endo form predominantly. The enthalpy difference between the C2'-endo form and the C3'-endo form of the
Marcus J O Johansson et al.
RNA (New York, N.Y.), 10(4), 712-719 (2004-03-24)
The biogenesis of transfer RNA is a process that requires many different factors. In this study, we describe a genetic screen aimed to identify gene products participating in this process. By screening for mutations lethal in combination with a sup61-T47:2C
Yu-Fang Zheng et al.
World journal of gastroenterology, 11(25), 3871-3876 (2005-07-02)
Fourteen urinary nucleosides, primary degradation products of tRNA, were evaluated to know the potential as biological markers for patients with colorectal cancer. The concentrations of 14 kinds of urinary nucleosides from 52 patients with colorectal cancer, 10 patients with intestinal
Yoshiho Ikeuchi et al.
The EMBO journal, 27(16), 2194-2203 (2008-08-01)
The wobble base of Escherichia coli elongator tRNA(Met) is modified to N(4)-acetylcytidine (ac(4)C), which is thought to ensure the precise recognition of the AUG codon by preventing misreading of near-cognate AUA codon. By employing genome-wide screen of uncharacterized genes in
Clement T Y Chan et al.
PLoS genetics, 6(12), e1001247-e1001247 (2010-12-29)
Decades of study have revealed more than 100 ribonucleoside structures incorporated as post-transcriptional modifications mainly in tRNA and rRNA, yet the larger functional dynamics of this conserved system are unclear. To this end, we developed a highly precise mass spectrometric
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