form
buffered aqueous solution
extent of labeling
3-6 mol biotin per mol annexin V
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... ANXA5(308)
Application
Can be used for detection of apoptotic cells in conjunction with streptavidin coupled to alkaline phosphatase, peroxidase, or FITC.
Biochem/physiol Actions
膜联蛋白是普遍存在的同源蛋白，在钙存在的情况下结合磷脂。
膜联蛋白是普遍存在的同源蛋白，在钙存在的情况下结合磷脂。参与凋亡过程的细胞变化包括早期磷脂不对称的损失。这种现象是普遍存在的，不局限于刺激或哺乳动物细胞，也发生在昆虫和植物细胞中。在活细胞中，磷脂酰丝氨酸通过Mg2+ATP依赖酶氨磷脂转位酶传输至脂二层内部。发生细胞凋亡时，磷脂酰丝氨酸转运到细胞膜的外表面。磷脂酰丝氨酸从内膜表面到外膜表面的移动是细胞凋亡的早期指标，膜联蛋白V及其偶联物与磷脂酰丝氨酸相互作用且具有较强的特异性，可用于检测细胞凋亡。膜联蛋白V偶联物可用于检测明显早于基于DNA分析的凋亡细胞。 荧光染料标记的膜联蛋白V可应用于流式细胞术、荧光显微镜和激光扫描细胞术中。
Physical form
Solution in 50 mM Tris-HCl, pH 7.5, containing 100 mM NaCl.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
相关内容
Instructions
Instructions
Chiara Falcicchia et al.
Brain communications, 5(3), fcad170-fcad170 (2023-06-08)
β-Amyloid is one of the main pathological hallmarks of Alzheimer's disease and plays a major role in synaptic dysfunction. It has been demonstrated that β-amyloid can elicit aberrant excitatory activity in cortical-hippocampal networks, which is associated with behavioural abnormalities. However
Yuxuan Zhang et al.
Computational and mathematical methods in medicine, 2022, 8388473-8388473 (2022-06-07)
As an important load-bearing part of the body, joints are prone to articular cartilage degradation during exercise, resulting in joint pain, swelling, and deformity, which has an adverse impact on patients' life quality and social medical security. Therefore, this study
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A7810-10UG | 04061833380222 |