A8606
Anti-α2C Adrenergic Receptor antibody produced in rabbit
~1 mg/mL, affinity isolated antibody, buffered aqueous solution
别名:
Anti-α-2-adrenergic receptor, renal type, Anti-ADRA2C, Anti-ADRA2L2, Anti-ALPHA2CAR
产品名称
Anti-α2C Adrenergic Receptor antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, rat, mouse
concentration
~1 mg/mL
technique(s)
immunohistochemistry: 1:100-1:300
western blot: 1:500-1:1,000
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ADRA2C(152)
mouse ... Adra2c(11553)
rat ... Adra2c(24175)
Application
Rabbit Anti-α2C Adrenergic Receptor antibody can be used for immunohistochemistry (1:100-1:300) and western blot (1:500-1:1,000) applications.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Adrenergic receptors are a G-protein coupled receptors that exist in two forms, α or β. Ligands for adrenergic receptors are catecholamines that induce a sympathetic response in animal cells.
Studies have reported that α2C adrenergic receptors can regulate adrenergic opioid synergy and spinal analgesia. Rabbit Anti-α2C Adrenergic Receptor antibody binds to humanα2C Adrenergic Receptor.
Immunogen
synthetic peptide corresponding to an internal sequence of human α2C Adrenergic Receptor.
Physical form
solution in phosphate buffered saline, containing 0.02% sodium azide.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
此项目有
Carolyn A Fairbanks et al.
The Journal of pharmacology and experimental therapeutics, 300(1), 282-290 (2001-12-26)
The alpha(2A)-adrenergic receptor (AR) subtype mediates antinociception induced by the alpha(2)AR agonists clonidine, dexmedetomidine, norepinephrine, and 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine (UK-14,304) as well as antinociceptive synergy of UK-14,304 with opioid agonists [D-Ala(2),N-Me-Phe(4),Gly(5)-ol]-enkephalin and deltorphin II. Differential localization of alpha(2)-adrenergic (alpha(2A)-, alpha(2B)-(,) alpha(2C)-) and
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