A8676
阿普洛尔 盐酸盐
≥98% (TLC), powder
别名:
1-(o-烯丙基苯氧基)-3-(异丙基氨基)-2-丙醇 盐酸盐
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C15H23NO2 · HCl
化学文摘社编号:
分子量:
285.81
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
237-244-4
MDL number:
产品名称
阿普洛尔 盐酸盐, ≥98% (TLC), powder
InChI key
RRCPAXJDDNWJBI-UHFFFAOYSA-N
InChI
1S/C15H23NO2.ClH/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3;/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3;1H
SMILES string
Cl[H].CC(C)NCC(O)COc1ccccc1CC=C
assay
≥98% (TLC)
form
powder
color
off-white
solubility
H2O: 50 mg/mL
Gene Information
human ... ADRB1(153), ADRB2(154)
正在寻找类似产品? 访问 产品对比指南
Application
Alprenolol is a nonselective β-blocker and a serotonin 5HT1A receptor antagonist.
Biochem/physiol Actions
β1- and β2-adrenoceptor antagonist.
A J Surman et al.
Journal of cardiovascular pharmacology, 21(1), 35-39 (1993-01-01)
We studied the effects of alprenolol and bromoacetylalprenololmenthane (BAAM) on rat left atria. Alprenolol and BAAM at 10(-7), 3 x 10(-7), and 10(-6) M inhibited the cardiac stimulation response slightly, which is indicative of membrane-stabilizing activity independent of beta-adrenoceptor blockade.
Noel Dew et al.
Colloids and surfaces. B, Biointerfaces, 89, 53-60 (2011-10-01)
To fully utilize the extended contact time of gel formulations a novel formulation with drug containing catanionic aggregates offering prolonged drug release and skin penetration were investigated. This study aimed to further explore the drug release process from catanionic vesicles
Marjukka Ikonen et al.
Colloids and surfaces. B, Biointerfaces, 78(2), 275-282 (2010-04-20)
In this work, isothermal titration calorimetry (ITC) combined with zeta potential measurements was used to study the binding and partitioning of three beta-blockers, alprenolol, labetalol and propranolol, and the local anaesthetic tetracaine into liposomes. The thermodynamic parameters of enthalpy, entropy
Y Shirayama et al.
European journal of pharmacology, 331(2-3), 319-323 (1997-07-23)
Desipramine, imipramine, clomipramine, (-)-propranolol, (-)-alprenolol, (+/-)-pentazocine and risperidone caused a concentration-dependent inhibition of 6 nM [3H]DTG (1,3-di-o-tolylguanidine)-defined sigma (sigma) binding with Ki values of about 0.5-2.5 microM in well-washed homogenates obtained from rat cerebral cortex. The saturation studies revealed that
(-)Alprenolol potentiates the disrupting effects of dizocilpine on sensorimotor function in the rat.
J Zhang et al.
Psychopharmacology, 132(3), 281-288 (1997-08-01)
The beta-adrenoceptor antagonist as well as serotonin 5-HT1 receptor antagonist, (-)alprenolol, was found to potentiate the disrupting effect of the noncompetitive NMDA receptor antagonist, dizocilpine, on prepulse inhibition (PPI) of the acoustic startle response (ASR) in the rat. The facilitating
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持