A8699
Activin Receptor IIA human
>95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder
生物来源
human
重组
expressed in baculovirus infected Sf21 cells
方案
>95% (SDS-PAGE)
表单
lyophilized powder
分子量
calculated mol wt 40 kDa
储存条件
avoid repeated freeze/thaw cycles
杂质
endotoxin, tested
UniProt登记号
储存温度
−20°C
基因信息
human ... ACVR2A(92)
生化/生理作用
Activin isoforms are members of the TGF-β superfamily that bind to heteromeric complexes of a type I and a type II serine/threonine kinase receptor, both of which are essential for signal transduction. In addition to the activin isoforms, activin receptor II binds inhibin, BMP-2 and BMP-7. Human, murine and rat type II activin receptors demonstrate greater than 98% homology.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5 mg bovine serum albumin.
分析说明
The biological activity is measured by its ability to inhibit hemoglobin expression induced by activin in K562 cells.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
L Attisano et al.
Molecular and cellular biology, 16(3), 1066-1073 (1996-03-01)
Activin exerts its effects by simultaneously binding to two types of p rotein serine/threonine kinase receptors, each type existing in various isoforms. Using the ActR-IB and ActR-IIB receptor isoforms, we have investigated the mechanism of activin receptor activation. ActR-IIB are
相关内容
Datasheet
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