Monoclonal Anti-Monoclonal Anti- AD (Alzheimer′s Disease) Tau 小鼠抗

Tau is an axonal protein that promotes microtubule assembly and stabilizes neuronal microtubules. Under pathological conditions, Tau can get hyperphosphorylated and form aberrant aggregates similar to those found in Alzheimer′s disease.

The antibody recognizes only human Alzheimer´s tau that is conformationally different from normal tau and shows no cross-reactivity with tau from age-matched control brains or with six recombinant tau isoforms, MAPs, or tubulin.

Alzheimer´s tau isolated from AD brain.

Autopsied human brains were formalin-fixed and paraffin-embedded then cut into 10 um sections for immunohistochemistry using monoclonal mouse anti-Alzheimer′s Disease Tau antibody at a dilution of 1:1000.

Mouse Monoclonal Anti-Alzheimer′s Disease Tau antibody has been used for immunohistochemical applications. The antibody can also be used for indirect immunofluorescence (1:1,000) and western blot (1:500) applications.

Solution in DMEM (without sodium pyruvate and sodium bicarbonate) containing 0.1% thimerosal as a preservative.

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.