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Merck
CN

A9052

Atrial Natriuretic Peptide chicken

≥95% (HPLC)

别名:

ANF 1-29

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经验公式(希尔记法):
C124H211N47O40S5
化学文摘社编号:
分子量:
3160.62
UNSPSC Code:
12352200
MDL number:
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assay

≥95% (HPLC)

UniProt accession no.

storage temp.

−20°C

Gene Information

chicken ... LOC395765(395765)

Biochem/physiol Actions

Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.

Preparation Note

Originally isolated from atrium.

Analysis Note

Has diuretic-natriuretic and hypotensive activity similar to mammalian ANF.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

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A Miyata et al.
Biochemical and biophysical research communications, 155(3), 1330-1337 (1988-09-30)
Morphological and pharmacological observations have suggested that chicken atrial natriuretic peptide (ANP) is different from mammalian ANP. The present survey for the as yet unidentified ANP in chicken heart was performed by monitoring the relaxant effect on chick rectum. From

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